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MBP 抗体

This anti-MBP antibody is a 兔 多克隆 antibody detecting MBP in WB 和 EIA. Suitable for 人 和 大鼠.
产品编号 ABIN318414
发货至: 中国

Quick Overview for MBP 抗体 (ABIN318414)

抗原

See all MBP 抗体
MBP (Myelin Basic Protein (MBP))

适用

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人, 大鼠

宿主

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  • 1

克隆类型

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多克隆

标记

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This MBP antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 特异性

    This antibody is specific for myelin basic protein (MBP), an abundant protein component of the myelin membrane and is reported to have a role in its formation and stabilisation.

    纯化方法

    Purified IgG prepared by affinity chromatography on Protein G

    免疫原

    Native Myelin Basic Protein from Human brain

    亚型

    IgG
  • 应用备注

    Western Blot: detects band at 18.5 kDa on reducing SDS-PAGE against rat brain lysate. ELISA: 1/100 - 1/400.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.0 mg/mL

    缓冲液

    Phosphate buffered saline containing 0.09 % Sodium Azide (NaN3)

    储存液

    Sodium azide

    注意事项

    This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    MBP (Myelin Basic Protein (MBP))

    别名

    Myelin Basic Protein

    背景

    The classic group of Myelin basic protein (MBP) isoforms (isoforms 4 to 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non classic group of MBP isoforms (isoforms 1 to 3/Golli MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T cells and neural cells. Differential splicing events combined to optional posttranslational modifications give a wide spectrum of isomers, each of them having maybe a specialized function.Synonyms: MBP, Myelin membrane encephalitogenic protein

    基因ID

    4155

    NCBI登录号

    NP_001020252

    UniProt

    P02686
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