MBP 抗体
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北京 101111
Quick Overview for MBP 抗体 (ABIN318414)
抗原
See all MBP 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody is specific for myelin basic protein (MBP), an abundant protein component of the myelin membrane and is reported to have a role in its formation and stabilisation.
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纯化方法
- Purified IgG prepared by affinity chromatography on Protein G
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免疫原
- Native Myelin Basic Protein from Human brain
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亚型
- IgG
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应用备注
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Western Blot: detects band at 18.5 kDa on reducing SDS-PAGE against rat brain lysate. ELISA: 1/100 - 1/400.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline containing 0.09 % Sodium Azide (NaN3)
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储存液
- Sodium azide
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注意事项
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- MBP (Myelin Basic Protein (MBP))
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别名
- Myelin Basic Protein
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背景
- The classic group of Myelin basic protein (MBP) isoforms (isoforms 4 to 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non classic group of MBP isoforms (isoforms 1 to 3/Golli MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T cells and neural cells. Differential splicing events combined to optional posttranslational modifications give a wide spectrum of isomers, each of them having maybe a specialized function.Synonyms: MBP, Myelin membrane encephalitogenic protein
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基因ID
- 4155
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NCBI登录号
- NP_001020252
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UniProt
- P02686
抗原
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