Uromodulin 抗体 (AA 329-378)
Quick Overview for Uromodulin 抗体 (AA 329-378) (ABIN3180922)
抗原
See all Uromodulin (UMOD) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 329-378
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原理
- Rabbit polyclonal antibody anti-Uromodulin (329-378 aa) is suitable for use in Western Blot, ELISA and Immunohistochemistry research applications.
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特异性
- THP Polyclonal Antibody detects endogenous levels of THP protein.
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产品特性
- Rabbit Polyclonal to THP.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from the human THP at the amino acid range 329-378
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亚型
- IgG
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anti-Uromodulin (UMOD) (AA 351-450) antibody
UMOD 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Uromodulin (UMOD) (AA 25-120) antibodyUMOD 适用: 人 WB, IP, ELISA 宿主: 小鼠 Monoclonal 3F10 unconjugated
anti-Uromodulin (UMOD) (AA 32-151) antibodyUMOD 适用: 犬 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Uromodulin (UMOD) (AA 1-611) antibodyUMOD 适用: 人 WB, IHC (p), IF 宿主: 小鼠 Polyclonal unconjugated
anti-Uromodulin (UMOD) (AA 1-611) antibodyUMOD 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Uromodulin (UMOD) (AA 334-589) antibodyUMOD 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Uromodulin (UMOD) antibodyUMOD 适用: 人, 犬 IHC, IHC (p), IF, IHC (fro) 宿主: 小鼠 Monoclonal 10-32 unconjugated
anti-Uromodulin (UMOD) (C-Term) antibodyUMOD 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Uromodulin (UMOD) (AA 335-590) antibodyUMOD 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Uromodulin (UMOD) (AA 30-150) antibodyUMOD 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000, ELISA 1:10000, IHC-P 1:50-300
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- -20 °C
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储存方法
- Store at -20°C.
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- Uromodulin (UMOD)
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别名
- UMOD
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背景
- Uromodulin: Functions in biogenesis and organization of the apical membrane of epithelial cells of the thick ascending limb of Henle's loop (TALH), where it promotes formation of complex filamentous gel-like structure that may play a role in the water barrier permeability (Probable). May serve as a receptor for binding and endocytosis of cytokines (IL-1, IL-2) and TNF. Facilitates neutrophil migration across renal epithelia. Uromodulin, secreted form: In the urine, may contribute to colloid osmotic pressure, retards passage of positively charged electrolytes, and inhibits formation of liquid containing supersaturated salts and subsequent formation of salt crystals. Protects against urinary tract infections by binding to type 1 fimbriated E.coli. Binds to bacterial adhesin fimH which mediates the stable formation of bacterial aggregates, prevents the binding of E.coli to uroplakins UPK1A and UPK1B which act as urothelial receptors for type I fimbriae, and allows for pathogen clearance through micturation. Also promotes aggregation of other bacteria including K.pneumoniae, P.aeruginosa and S.mitis and so may also protect against other uropathogens.
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分子量
- 70 kDa
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基因ID
- 7369
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UniProt
- P07911
抗原
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