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MT-ND1 抗体

The 兔 多克隆 anti-MT-ND1 antibody (ABIN317922) specifically detects MT-ND1 in WB 和 IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN317922
发货至: 中国
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Quick Overview for MT-ND1 抗体 (ABIN317922)

抗原

See all MT-ND1 抗体
MT-ND1 (Mitochondrially Encoded NADH Dehydrogenase 1 (MT-ND1))

适用

  • 27
  • 9
  • 5

宿主

  • 28
  • 2

克隆类型

  • 27
  • 3
多克隆

标记

  • 20
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This MT-ND1 antibody is un-conjugated

应用范围

  • 20
  • 12
  • 12
  • 5
  • 5
  • 4
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 特异性

    This antibody detects endogenous levels of ND1 protein.(region surrounding Val208)

    纯化方法

    Affinity Chromatography using epitope-specific immunogen
  • 应用备注

    ELISA: 1/40000approx. 1/60000. Western Blot: 1/500approx. 1/1000. Immunohistochemistry: 1/50approx. 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH ~7.2, 15 mM Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    MT-ND1 (Mitochondrially Encoded NADH Dehydrogenase 1 (MT-ND1))

    别名

    ND1

    背景

    NADH:ubiquinone oxidoreductase (complex I) is an extremely complicated multiprotein complex located in the inner mitochondrial membrane. Human complex I is important for energy metabolism because its main function is to transport electrons from NADH to ubiquinone, which is accompanied by translocation of protons from the mitochondrial matrix to the intermembrane space. Human complex I appears to consist of 41 subunits. A small number of complex I subunits are the products of mitochondrial genes (subunits 1-7),while the remainder are nuclear encoded and imported from the cytoplasm. NADH dehydrogenase subunit 1 (ND1) binds rotenone and rotenone analogs and might be involved in electron transfer to ubiquinone. Mutations in the ND1 gene may be implicated in several disorders, including Leber hereditary optic neuropathy, Alzheimer's disease and Parkinson disease.Synonyms: MT-ND1, MTND1, NADH-ubiquinone oxidoreductase chain 1, NADH1

    分子量

    approx. 40.0 kDa

    基因ID

    4535

    NCBI登录号

    YP_003024026

    UniProt

    P03886
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