Six5 抗体
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北京 101111
Quick Overview for Six5 抗体 (ABIN317916)
抗原
See all Six5 (SIX5) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Six5 antibody detects endogenous levels of Six5 protein.(region surrounding Leu237)
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纯化方法
- Affinity chromatography
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anti-Homeobox protein SIX5 (SIX5) (AA 257-286) antibody
SIX5 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB32413 unconjugated
anti-Homeobox protein SIX5 (SIX5) (C-Term) antibodySIX5 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Homeobox protein SIX5 (SIX5) antibodySIX5 适用: 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Homeobox protein SIX5 (SIX5) (AA 1-170) antibodySIX5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Homeobox protein SIX5 (SIX5) (Internal Region) antibodySIX5 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Homeobox protein SIX5 (SIX5) (Internal Region) antibodySIX5 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Homeobox protein SIX5 (SIX5) (AA 264-294), (Middle Region) antibodySIX5 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1: 40000approx. 1: 60000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Six5 (SIX5) (Homeobox protein SIX5 (SIX5))
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别名
- SIX5
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背景
- Six5 (homeobox protein SIX5), also known as SIX5, BOR2 or DMAHP (DM locus-associated homeodomain protein), is a transcription factor that is expressed in various structures of the adult eye. Localized to the cytoplasm in early development and to the nucleus in the later stages of development,Six5 is involved in regulation of organogenesis and in maintenance of retinal formation. Six5 is able to bind the 5'-TCA[AG][AG]TTNC-3' DNA sequence found in the myogenin and IGFBP5 promoters and, through this binding, can control transcription of the associated mRNA. Six5 is regulated via association with DACH1 (dachshund homolog 1) and is co-activated by the EYA (eyes absent) proteins. Defects in the gene encoding Six5 are the cause of branchiooto- renal syndrome type 2 (BOR2), an autosomal disorder characterized by hearing loss, a deep overbite and myopia. Two isoforms exist due to alternative splicing events.Synonyms: DM locus-associated homeodomain protein, DMAHP, Homeobox protein SIX5, Sine oculis homeobox homolog 5
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分子量
- approx. 75 kDa
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基因ID
- 147912
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NCBI登录号
- NP_787071
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UniProt
- Q8N196
抗原
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