FUBP3 抗体
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北京 101111
Quick Overview for FUBP3 抗体 (ABIN317906)
抗原
See all FUBP3 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of FBP3 protein.(region surrounding Arg241)
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交叉反应 (详细)
- Species reactivity (tested):Human, Mouse, Rat.
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纯化方法
- Affinity Chromatography using epitope-specific immunogen
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应用备注
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ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- FUBP3 (Far Upstream Element (FUSE) Binding Protein 3 (FUBP3))
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别名
- FUBP3
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背景
- Activation of FUSE, the far-upstream element, is required for the proper expression of the mammalian gene c-Myc in undifferentiated cells. The binding of FBP (FUSE-binding protein) to FUSE is necessary for c-Myc expression, indicating that FBP functions as a growth-dependent regulator of c-Myc expression. Isolated from proliferating HL60 cells, FBP, FBP2, and FBP3 comprise a family of single-stranded DNA-binding proteins that specifically bind to FUSE elements. The FBP transcription factors share a conserved central DNA-binding domain and show significant homology in their carboxylterminal activation domains. Expression of FBP is detected in undifferentiated cells and is substantially decreased following cellular differentiation.Synonyms: FBP3, FUSE-binding protein 3, Far upstream element-binding protein 3
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分子量
- approx. 60 kDa
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基因ID
- 8939
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NCBI登录号
- NP_003925
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UniProt
- Q96I24
抗原
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