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CPN1 抗体

The 兔 多克隆 anti-CPN1 antibody is suitable to detect CPN1 in samples from 人. It has been validated for WB.
产品编号 ABIN317900
发货至: 中国
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Quick Overview for CPN1 抗体 (ABIN317900)

抗原

See all CPN1 抗体
CPN1 (Carboxypeptidase N Subunit 1 (CPN1))

适用

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宿主

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克隆类型

  • 39
多克隆

标记

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This CPN1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 特异性

    CPN cat antibody detects endogenous levels of CPN cat protein.(region surrounding Gln452)

    纯化方法

    Affinity chromatography
  • 应用备注

    ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1,0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    CPN1 (Carboxypeptidase N Subunit 1 (CPN1))

    别名

    Carboxypeptidase N Catalytic Chain

    背景

    Carboxypeptidase N (arginine carboxypeptidase or CPN) cleaves basic amino acid residues from the carboxy terminal of peptides and proteins. The enzyme plays a central role in regulating the biologic activity of peptides such as kinins and anaphylatoxins, and therefore is also known as kininase-1 and anaphylatoxin inactivator. CPN is a tetrameric complex consisting of two identical regulatory subunits (CPN reg) and two identical catalytic subunits (CPN cat). The two glycosylated CPN reg subunits protect the two CPN cat subunits and keep them in the circulation. CPN reg is a member of the leucinerich repeat family of proteins and the gene which encodes CPN reg maps to human chromosome 8p22-p23. CPN cat is a member of the regulatory B-type carboxypeptidase group and the gene which encodes CPN cat maps to human chromosome 10.Synonyms: ACBP, Anaphylatoxin inactivator, Arginine carboxypeptidase, CPN, CPN1, Carboxypeptidase N polypeptide 1, Carboxypeptidase N small subunit, Kininase-1, Lysine carboxypeptidase, Plasma carboxypeptidase B, SCPN, Serum carboxypeptidase N

    分子量

    approx. 52 kDa

    基因ID

    1369

    NCBI登录号

    NP_001299

    UniProt

    P15169

    途径

    Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, C21-Steroid Hormone Metabolic Process
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