AVPR2 抗体
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北京 101111
Quick Overview for AVPR2 抗体 (ABIN317870)
抗原
See all AVPR2 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of AVP Receptor V2 protein.(region surrounding Leu111)
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纯化方法
- Affinity Chromatography using epitope-specific immunogen.
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anti-Arginine Vasopressin Receptor 2 (AVPR2) (C-Term) antibody
AVPR2 适用: 人, 猴, Cow, 犬, 豚鼠, 绵羊 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Arginine Vasopressin Receptor 2 (AVPR2) (AA 221-271) antibodyAVPR2 适用: 人 ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Arginine Vasopressin Receptor 2 (AVPR2) antibodyAVPR2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Arginine Vasopressin Receptor 2 (AVPR2) (C-Term) antibodyAVPR2 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, 绵羊, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-Arginine Vasopressin Receptor 2 (AVPR2) (AA 343-377), (C-Term) antibodyAVPR2 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB52186 unconjugated
anti-Arginine Vasopressin Receptor 2 (AVPR2) (Internal Region) antibodyAVPR2 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Arginine Vasopressin Receptor 2 (AVPR2) (Cytoplasmic Domain) antibodyAVPR2 适用: 人, 小鼠, 大鼠, 猴, 兔, Hamster IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Arginine Vasopressin Receptor 2 (AVPR2) (C-Term) antibodyAVPR2 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Arginine Vasopressin Receptor 2 (AVPR2) (AA 65-170) antibodyAVPR2 适用: 小鼠 WB, ELISA, IF (cc), IF (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate Buffered Saline (PBS), pH ~7.2 with 0.05 % Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- AVPR2 (Arginine Vasopressin Receptor 2 (AVPR2))
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别名
- Vasopressin V2 Receptor (AVPR2)
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背景
- Vasopressin (AVP), the antidiuretic hormone, is a cyclic nonpeptide that is involved in the regulation of body fluid osmolality. AVP mediates its effects through a family of G-protein coupled receptors, the vasopressin receptors type V1a, V2 and V3 (also designated V1b). The AVP receptor V1a is responsible for several functions, including blood vessel constriction, liver glycogenolysis and platelet adhesion. It is detected as a full length protein and a shorter protein, which results from proteolytic cleavage of its amino terminus. The V1a receptor is coupled to Gq/11 protein, which increases the intracellular calcium concentration. The human AVP receptor V2 gene maps to chromosome Xq28 and is expressed in lung and kidney. Mutations in the V2 receptor result in nephrogenic diabetes insipidus (NDI), a rare X-linked disorder characterized by the inability of the kidney to concentrate urine in response to AVP. The AVP Receptor V2 activates the Gs protein and the cyclic AMP second messenger system. The AVP Receptor V3 is preferentially expressed in the pituitary and stimulates the release of adrenocorticotropic hormone (ACTH) in response to AVP by mobilizing intracellular calcium stores. AVP receptor antagonists may have potential therapeutic effects in hypertension, congestive heart failure, nephrotic syndrome and ACTH-secreting tumors.Synonyms: ADHR, AVPR V2, Antidiuretic hormone receptor, DIR, DIR3, Renal-type arginine vasopressin receptor, V2R
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分子量
- approx. 38 kDa
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基因ID
- 554
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NCBI登录号
- NP_000045
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UniProt
- P30518
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途径
- cAMP Metabolic Process
抗原
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