QRFPR 抗体
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北京 101111
Quick Overview for QRFPR 抗体 (ABIN317864)
抗原
See all QRFPR 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- GPR103 antibody detects endogenous levels of GPR 103 protein.(region surrounding Ile310)
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纯化方法
- Affinity Chromatography using epitope-specific immunogen
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应用备注
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ELISA: 1/10000approx. 1/20000. Western Blot: 1/500approx. 1/1000. Immunofluorescence: 1/50approx. 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH ~7.2 with 0.05 % Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- QRFPR (Pyroglutamylated RFamide Peptide Receptor (QRFPR))
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别名
- QRFPR / GPR103
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背景
- G protein-coupled receptors (GPRs) are a protein family of transmembrane receptors that transmit an extracellular signal (ligand binding) into an intracellular signal (G protein activation). GPR signaling is an evolutionarily ancient mechanism used by all eukaryotes to sense environmental stimuli and mediate cell-cell communication. All of the receptors have seven membrane-spanning domains and the extracellular parts of the receptor can be glycosylated. These extracellular loops also contain two highly conserved cysteine residues which create disulfide bonds to stabilize the receptor structure. GPR103 is a 455 amino acid protein with highest expression in the brain, retina, trigeminal ganglion, hypothalamus and vestibular nucleus. In peripheral tissues, GPR103 is expressed only in the heart, kidney and testis. GPR103 may regulate adrenal function. A hypothalamic neuropeptide of the RFamide family (26RFa) acts as an endogenous ligand for GPR103.Synonyms: AQ27, G-protein coupled receptor 103, Orexigenic neuropeptide QRFP receptor, Pyroglutamylated RFamide peptide receptor, SP9155
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分子量
- approx. 49 kDa
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基因ID
- 84109
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NCBI登录号
- NP_937822
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UniProt
- Q96P65
抗原
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