DRD4 抗体
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北京 101111
Quick Overview for DRD4 抗体 (ABIN317857)
抗原
See all DRD4 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- D4DR antibody detects endogenous levels of D4DR protein.(region surrounding Leu396)
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纯化方法
- Affinity Chromatography using epitope-specific immunogen.
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应用备注
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ELISA: 1/40000-1/60000. Western Blot: 1/500-1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH ~7.2 containing 15 mM Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- DRD4 (Dopamine Receptor D4 (DRD4))
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别名
- Dopamine D4 Receptor
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背景
- This gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in this gene have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. This gene contains a polymorphic number (2-10 copies) of tandem 48 nt repeats, the sequence shown contains four repeats.DRD4 expression has been reported in various regions of the brain as well as in adrenal gland, artery, eye, heart, kidney, placenta, spinal cord, testis, and vas deferens.Synonyms: D(2C) dopamine receptor, D(4) dopamine receptor, DRD4
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分子量
- approx. 50 kDa
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基因ID
- 1815
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NCBI登录号
- NP_000788
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UniProt
- P21917
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途径
- cAMP Metabolic Process, Synaptic Membrane, Proton Transport, Photoperiodism, Negative Regulation of Transporter Activity
抗原
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