ADRB3 抗体
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北京 101111
Quick Overview for ADRB3 抗体 (ABIN317855)
抗原
See all ADRB3 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- AR-β3 antibody detects endogenous levels of AR-β3 protein.(region surrounding Leu291)
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纯化方法
- Affinity chromatography
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应用备注
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ELISA: 1: 5000approx. 1: 10000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- ADRB3 (Adrenergic, beta-3-, Receptor (ADRB3))
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别名
- beta-3 Adrenergic Receptor
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背景
- The members of the G-protein-coupled receptor family are distinguished by their slow transmitting response to ligand binding. These seven transmembrane proteins include the adrenergic, serotonin and dopamine receptors. The effect of the signaling molecule can be excitatory or inhibitory depending on the type of receptor to which it binds. β-adrenergic bound to adrenaline activates adenylyl cyclase, while α2-adrenergic receptor bound to adrenaline inhibits adenylyl cyclase. Like the α2-adrenergic receptor, serotonin receptor functions are also mediated by G proteins that inhibit the activity of adenylyl cyclase. The serotonin receptors have been classified into several categories and they are designated 5-HT1, 5-HT2, 5-HT3, 5-HT4, 5-HT5, 5-HT6 and 5-HT7. The 5-HT1 receptors have further been subdivided into 5-HT1A, 5-HT1B, 5-HT1C, 5-HT1D, 5-HT1E and 5-HT1F receptors.Synonyms: ADRB3, ADRB3R, B3AR, Beta-3 adrenoceptor
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分子量
- approx. 36 kDa
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基因ID
- 155
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NCBI登录号
- NP_000016
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UniProt
- P13945
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途径
- cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Feeding Behaviour, Brown Fat Cell Differentiation
抗原
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