ABCC10 抗体
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北京 101111
Quick Overview for ABCC10 抗体 (ABIN317845)
抗原
See all ABCC10 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- MRP7 antibody detects endogenous levels of MRP7 protein.(region surrounding Glu865)
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纯化方法
- Affinity chromatography
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应用备注
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ELISA: 1: 40000approx. 1: 60000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- ABCC10 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 10 (ABCC10))
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别名
- ABCC10 / MRP7
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背景
- The MRP family is represented by nine similar ABC transporters that have the ability to transport structurally diverse lipophilic anions and operate as chemical efflux pumps. MRP7 (multidrug resistance-associated protein 7, ATPbinding cassette sub-family C member 10) is a multi-pass membrane protein that belongs to the ABC transporter family (conjugate transporter subfamily). MRP7 is involved with the ATP-dependent transport of 17β-estradiol-D-17-β-glucuronide (E217βG). MRP7 is also probably involved in cellular detoxification through its lipophilic anion extrusion capabilities. MRP7 contains two ABC transmembrane type 1 domains and two ABC transporter domains. MRP7 likely has three isoforms. Isoform 2 is the most widely expressed, while isoform 1 is predominately expressed in the spleen.Synonyms: ATP-binding cassette, Multidrug resistance-associated protein 7, SIMRP7, member 10, sub-family C
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分子量
- approx. 162 kDa
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基因ID
- 89845
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NCBI登录号
- NP_001185863
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UniProt
- Q5T3U5
抗原
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