REM1 抗体
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北京 101111
Quick Overview for REM1 抗体 (ABIN317842)
抗原
See all REM1 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of Rad GTPase protein.(region surrounding Leu80)
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Affinity Chromatography using epitope-specific immunogen
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anti-RAS (RAD and GEM)-Like GTP-Binding 1 (REM1) (N-Term) antibody
REM1 适用: 人 WB, ELISA, IF, ICC, IHC 宿主: 兔 Polyclonal unconjugated
anti-RAS (RAD and GEM)-Like GTP-Binding 1 (REM1) (AA 1-298) antibodyREM1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-RAS (RAD and GEM)-Like GTP-Binding 1 (REM1) (AA 2-153) antibodyREM1 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-RAS (RAD and GEM)-Like GTP-Binding 1 (REM1) (AA 71-120) antibodyREM1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 绵羊, 斑马鱼, Bat, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- REM1 (RAS (RAD and GEM)-Like GTP-Binding 1 (REM1))
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别名
- REM1
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背景
- The Ras-encoded family of proteins bind GDP and GTP with high affinity. They possess a low level of intrinsic GTPase activity that increases more than 100-fold when interacting with cytosolic GTPase activating protein (GAP). Ras family members include H-Ras, K-Ras, N-Ras, M-Ras, R-Ras, ERas, Rheb, TC 21, RASL11B and Rad (Ras associated with diabetes) GTPase.Rad GTPase is a GTP-binding protein that is similar to Ras but has unique features. Unlike other small GTPases, Rad GTPase lacks typical pren-ylation motifs at its C terminus. The Rad GTPase enzyme binds calmodulin, inhibits vascular lesion formation, has low intrinsic GTPase activity and cannot be stimulated by any known GAP molecules. Rad GTPase is expressed in skeletal muscle, cardiac muscle and lung tissues and is overexpressed in the skeletal muscle tissue of individuals with type II diabetes.Synonyms: GES, GTP-binding protein REM 1, GTPase-regulating endothelial cell sprouting, REM, Rad and Gem-like GTP-binding protein 1
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分子量
- approx. 33 kDa
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基因ID
- 28954
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NCBI登录号
- NP_054731
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UniProt
- O75628
抗原
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