GRB14 抗体
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北京 101111
Quick Overview for GRB14 抗体 (ABIN317840)
抗原
See all GRB14 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- GRB14 antibody detects endogenous levels of GRB14 protein.(region surrounding Asp123)
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纯化方法
- Affinity chromatography
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anti-Growth Factor Receptor-Bound Protein 14 (GRB14) (AA 14-48) antibody
GRB14 适用: 人 WB, IF, FACS 宿主: 兔 Polyclonal RB57897 unconjugated
anti-Growth Factor Receptor-Bound Protein 14 (GRB14) (AA 294-397) antibodyGRB14 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Growth Factor Receptor-Bound Protein 14 (GRB14) (Internal Region) antibodyGRB14 适用: 人, 小鼠, 大鼠 ELISA, WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Growth Factor Receptor-Bound Protein 14 (GRB14) (AA 221-320) antibodyGRB14 适用: 人 ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Growth Factor Receptor-Bound Protein 14 (GRB14) (AA 251-300) antibodyGRB14 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Growth Factor Receptor-Bound Protein 14 (GRB14) (Internal Region) antibodyGRB14 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Growth Factor Receptor-Bound Protein 14 (GRB14) antibodyGRB14 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1: 40000approx. 1: 60000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- GRB14 (Growth Factor Receptor-Bound Protein 14 (GRB14))
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别名
- GRB14
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背景
- Many growth factors function by binding receptors with intrinsic tyrosine kinase activity. Signaling by such receptors involves a series of intermediates characterized by SH2 domains that bind tyrosine phosphorylated receptors by a direct interaction between the SH2 domain and specific phosphotyrosine-containing receptor sequences. GRB7, a SH2 domain protein, has a single SH2 domain at its C-terminal, a central region with similarity to Ras GAP and a proline-rich N terminus. A related SH2 domain-containing protein, GRB10, exhibits a high degree of homology with GRB7. GRB10 undergoes serine but not tyrosine phosphorylation in response to EGF treatment, but appears to bind to the EGF receptor poorly. An additional member of the GRB7 family, designated GRB14, contains a pleckstrin homology domain in its central region and a carboxy terminal SH2 domain.Synonyms: GRB14 adapter protein, Growth factor receptor-bound protein 14
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分子量
- approx. 61 kDa
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基因ID
- 2888
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NCBI登录号
- NP_004481
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UniProt
- Q14449
抗原
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