DNAJB11 抗体
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北京 101111
Quick Overview for DNAJB11 抗体 (ABIN317830)
抗原
See all DNAJB11 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- ERdj3 antibody detects endogenous levels of ERdj3 protein.(region surrounding Lys66)
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纯化方法
- Affinity chromatography
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anti-DnaJ (Hsp40) Homolog, Subfamily B, Member 11 (DNAJB11) (AA 89-358) antibody
DNAJB11 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-DnaJ (Hsp40) Homolog, Subfamily B, Member 11 (DNAJB11) antibodyDNAJB11 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-DnaJ (Hsp40) Homolog, Subfamily B, Member 11 (DNAJB11) (AA 53-238) antibodyDNAJB11 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-DnaJ (Hsp40) Homolog, Subfamily B, Member 11 (DNAJB11) (N-Term) antibodyDNAJB11 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-DnaJ (Hsp40) Homolog, Subfamily B, Member 11 (DNAJB11) (Internal Region) antibodyDNAJB11 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-DnaJ (Hsp40) Homolog, Subfamily B, Member 11 (DNAJB11) (AA 25-130) antibodyDNAJB11 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-DnaJ (Hsp40) Homolog, Subfamily B, Member 11 (DNAJB11) (C-Term) antibodyDNAJB11 适用: 人, 犬, Cow, 豚鼠, 马, 斑马鱼, Bat, 小鸡, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-DnaJ (Hsp40) Homolog, Subfamily B, Member 11 (DNAJB11) (Center) antibodyDNAJB11 适用: 人, 大鼠 IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-DnaJ (Hsp40) Homolog, Subfamily B, Member 11 (DNAJB11) antibodyDNAJB11 适用: 人, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-DnaJ (Hsp40) Homolog, Subfamily B, Member 11 (DNAJB11) (AA 63-92), (N-Term) antibodyDNAJB11 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB32154 unconjugated
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应用备注
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ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- DNAJB11 (DnaJ (Hsp40) Homolog, Subfamily B, Member 11 (DNAJB11))
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别名
- DNAJB11
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背景
- Members of the heat shock protein 40 (HSP 40) family of proteins all contain a highly conserved J domain that associates with HSP 70 and regulates the function of HSP 70 by activating its adenosine triphosphatase activity. ERdj3, an HSP 40 chaperone, is expressed in the ER lumen, where it interacts with BiP, a molecule involved in retrotranslocating proteins out of the ER. ERdj3 also associates with several other protein substrates, including unfolded light chains, a nonsecreted Ig light chain mutant and a VSV-G ts045 mutant. Shiga toxin (Stx) is a bacterial tool that enzymatically inactivates the 28S rRNA, inhibiting protein synthesis of infected cells. Stx also interacts with ERdj3 and Sec 61 to form a complex through which proteins are retrotranslocated to the cytoplasm. ERdj3 may play a role in the ER quality control system.Synonyms: APOBEC1-binding protein 2, DnaJ homolog subfamily B member 11, EDJ, ER-associated DNAJ, ER-associated Hsp40 co-chaperone, ER-associated dnaJ protein 3, ERJ3, ERdj3, ERj3p, HEDJ, PSEC0121, PWP1-interacting protein 4, hDj9
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分子量
- approx. 40 kDa
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基因ID
- 51726
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NCBI登录号
- NP_057390
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UniProt
- Q9UBS4
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途径
- ER-Nucleus Signaling
抗原
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