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APOL1 抗体

The 兔 多克隆 anti-APOL1 antibody (ABIN317817) specifically detects APOL1 in WB 和 IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN317817
发货至: 中国
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Quick Overview for APOL1 抗体 (ABIN317817)

抗原

See all APOL1 抗体
APOL1 (Apolipoprotein L, 1 (APOL1))

适用

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宿主

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克隆类型

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多克隆

标记

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This APOL1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 特异性

    ApoL1 antibody detects endogenous levels of ApoL1 protein.(region surrounding Gln294)

    纯化方法

    Affinity chromatography
  • 应用备注

    ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1,0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    APOL1 (Apolipoprotein L, 1 (APOL1))

    别名

    Apolipoprotein L1 (Apo L1)

    背景

    Apolipoproteins are protein components of plasma lipoproteins. The apolipoprotein L gene family encodes six highly homologous proteins designated apoL-I to -VI, which are associated with large high density type lipoproteins (HDL). The human apoL family maps to chromosome 22q12.1- 13.1 within a 127,000-bp region . apoL has been characterized as a pancreas specific, 383-amino acid, 42 kDa protein that contains a 12-amino acid secretory signal peptide. The apoL genes have TATA-less promoters and contain putative sterol regulatory elements, suggesting that transcription of these genes may be coordinated with that of the low density lipoprotein receptor and genes in pathways involving the synthesis of triglycerides and cholesterol. apoL homologs can undergo 10 fold changes in expression during atherosclerotic changes in vascular endothelial cells, which includes the inflammatory reaction of atherosclerotic lesions.Synonyms: APOL1, ApoL-I, Apolipoprotein L-I

    分子量

    approx. 44 kDa

    基因ID

    8542

    NCBI登录号

    NP_001130012

    UniProt

    O14791
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