GNaZ 抗体
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北京 101111
Quick Overview for GNaZ 抗体 (ABIN317793)
抗原
See all GNaZ 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Gz-α antibody detects endogenous levels of Gz-α protein.(region surrounding Ala12)
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纯化方法
- Affinity chromatography
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应用备注
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ELISA: 1: 5000approx. 1: 10000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- GNaZ (Guanine Nucleotide Binding Protein (G Protein), alpha Z Polypeptide (GNaZ))
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别名
- G Protein Z alpha
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背景
- Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. G proteins are composed of 3 units, alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site. G protein z alpha, encoded by the GNAZ gene, is enriched in neural tissue and differs in sequence from other G alpha subunits. Alpha Subunits are encoded in 15 genes and several transcripts are alternatively spliced. Receptors may discriminate between splice variants, whether splice variants are functionally different in regulating effectors is not known. All alpha subunits appear to be palmitoylated near the N-terminus.Synonyms: G(x) alpha chain, GNAZ, Guanine nucleotide-binding protein G(z) subunit alpha, Gz-alpha
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分子量
- approx. 41 kDa
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基因ID
- 2781
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NCBI登录号
- NP_002064
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UniProt
- P19086
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途径
- G-protein mediated Events
抗原
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