AVPR1B 抗体
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北京 101111
Quick Overview for AVPR1B 抗体 (ABIN317776)
抗原
See all AVPR1B 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- AVP Receptor V3 antibody detects endogenous levels of AVP Receptor V3 protein.
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纯化方法
- Affinity chromatography
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anti-Arginine Vasopressin Receptor 1B (AVPR1B) (N-Term) antibody
AVPR1B 适用: 人, 大鼠, 犬, Cow, Pig, 马, 兔, Bat IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Arginine Vasopressin Receptor 1B (AVPR1B) (Cytoplasmic Domain) antibodyAVPR1B 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Arginine Vasopressin Receptor 1B (AVPR1B) antibodyAVPR1B 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Arginine Vasopressin Receptor 1B (AVPR1B) (AA 224-284) antibodyAVPR1B 适用: 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Arginine Vasopressin Receptor 1B (AVPR1B) (AA 343-425) antibodyAVPR1B 适用: 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Arginine Vasopressin Receptor 1B (AVPR1B) (AA 271-320) antibodyAVPR1B 适用: 人, 大鼠, 小鼠, 犬, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Arginine Vasopressin Receptor 1B (AVPR1B) (C-Term) antibodyAVPR1B 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Arginine Vasopressin Receptor 1B (AVPR1B) antibodyAVPR1B 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Arginine Vasopressin Receptor 1B (AVPR1B) (AA 216-242) antibodyAVPR1B 适用: 小鼠 WB 宿主: 兔 Polyclonal RB38663 unconjugated
anti-Arginine Vasopressin Receptor 1B (AVPR1B) (AA 289-317), (C-Term) antibodyAVPR1B 适用: 人 WB 宿主: 兔 Polyclonal RB34126 unconjugated
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应用备注
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ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- AVPR1B (Arginine Vasopressin Receptor 1B (AVPR1B))
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别名
- Vasopressin V1b Receptor (V1bR)
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背景
- Vasopressin (AVP), the antidiuretic hormone, is a cyclic nonpeptide that is involved in the regulation of body fluid osmolality. AVP mediates its effects through a family of G protein coupled receptors, the vasopressin receptors type V1a, V2 and V3 (also designated V1b). The AVP receptor V1a is responsible for several functions, including blood vessel constriction, liver glycogenolysis and platelet adhesion. It is detected as an 85-90 kDa full length protein and a 46 kDa protein, which results from proteolytic cleavage of its amino terminus. The V1a receptor is coupled to Gq/11 protein, which increases the intracellular calcium concentration. The human AVP receptor V2 gene maps to chromosome Xq28 and is expressed in lung and kidney. Mutations in the V2 receptor result in nephrogenic diabetes insipidus (NDI), a rare X-linked disorder characterized by the inability of the kidney to concentrate urine in response to AVP. The AVP Receptor V2 activates the Gs protein and the cyclic AMP second messenger system. The AVP receptor V3 is preferentially expressed in the pituitary and stimulates the release of adrenocorticotropic hormone (ACTH) in response to AVP by mobilizing intracellular calcium stores. AVP receptor antagonists may have potential therapeutic effects in hypertension, congestive heart failure, nephrotic syndrome and ACTH-secreting tumors.Synonyms: AVPR V1b, AVPR V3, Antidiuretic hormone receptor 1b, Avpr1b, Vasopressin V3 receptor
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分子量
- approx. 47 kDa
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基因ID
- 553
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NCBI登录号
- NP_000698
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UniProt
- P47901
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途径
- Regulation of Systemic Arterial Blood Pressure by Hormones
抗原
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