RXFP2 抗体
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Quick Overview for RXFP2 抗体 (ABIN317772)
抗原
See all RXFP2 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of Relaxin Receptor 2 protein.
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交叉反应 （详细）
- Species reactivity (tested):Human, Mouse.
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纯化方法
- Affinity Chromatography using epitope-specific immunogen
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anti-Relaxin/insulin-Like Family Peptide Receptor 2 (RXFP2) (AA 33-158) antibody
RXFP2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Relaxin/insulin-Like Family Peptide Receptor 2 (RXFP2) (N-Term) antibodyRXFP2 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Relaxin/insulin-Like Family Peptide Receptor 2 (RXFP2) (Cytoplasmic Domain) antibodyRXFP2 适用: 人, 小鼠, 马 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Relaxin/insulin-Like Family Peptide Receptor 2 (RXFP2) (Extracellular Domain) antibodyRXFP2 适用: 人, 小鼠 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Relaxin/insulin-Like Family Peptide Receptor 2 (RXFP2) (Internal Region) antibodyRXFP2 适用: 人, 小鼠, 大鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Relaxin/insulin-Like Family Peptide Receptor 2 (RXFP2) (AA 692-721), (C-Term) antibodyRXFP2 适用: 人 WB 宿主: 兔 Polyclonal RB39323 unconjugated
anti-Relaxin/insulin-Like Family Peptide Receptor 2 (RXFP2) antibodyRXFP2 适用: 人 WB, FACS 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- RXFP2 (Relaxin/insulin-Like Family Peptide Receptor 2 (RXFP2))
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别名
- Relaxin Receptor 2 / RXFP2
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背景
- Relaxins are endocrine and autocrine/paracrine hormones belonging to the insulin gene superfamily. In several mammalian species, relaxin is best known for its role during pregnancy and parturition, when it is produced by the corpora lutea of ovaries and other reproductive tissues. The secretion of relaxin into the blood stream just before parturition results in a marked softening and lengthening of the pubic symphysis and a softening of the cervix, which facilitates the birth process. Also, by inhibiting uterine contractions, relaxin may influence the timing of parturition. Two previously characterized orphan receptors designated relaxin receptor 1 (LGR7) and 2 (LGR8) bind relaxin in several tissues, including reproductive tissues, brain, and heart. Upon ligand binding, the relaxin receptors activate adenylate cyclases through Gs proteins. Expression of the relaxin receptors in tissues other than reproductive ones suggests that they have additional physiological functions, such as regulating blood pressure and controlling vascular volume in the heart.Synonyms: G-protein coupled receptor 106, G-protein coupled receptor affecting testicular descent, GPR106, GREAT, LGR8, Leucine-rich repeat-containing G-protein coupled receptor 8, Relaxin family peptide receptor 2
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分子量
- approx. 86 kDa
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基因ID
- 122042
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NCBI登录号
- NP_570718
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UniProt
- Q8WXD0
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途径
- cAMP Metabolic Process, Myometrial Relaxation and Contraction
抗原
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