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Melatonin Receptor 1B 抗体

This 兔 多克隆 anti-Melatonin Receptor 1B antibody specifically detects Melatonin Receptor 1B in WB 和 EIA. The antibody is reactive with 人 samples.
产品编号 ABIN317757
发货至: 中国
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Quick Overview for Melatonin Receptor 1B 抗体 (ABIN317757)

抗原

See all Melatonin Receptor 1B (MTNR1B) 抗体
Melatonin Receptor 1B (MTNR1B)

适用

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宿主

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克隆类型

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多克隆

标记

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This Melatonin Receptor 1B antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 特异性

    This antibody detects endogenous levels of MEL-1B-R protein.

    纯化方法

    Affinity Chromatography using epitope-specific immunogen
  • 应用备注

    ELISA: 1/1000approx. 1/5000. Western blot: 1/500approx. 1/1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    Melatonin Receptor 1B (MTNR1B)

    别名

    Melatonin Receptor 1B

    背景

    The melatonin receptors, MEL-1A-R and MEL-1B-R, are members of the superfamily of guanine nucleotide-binding regulatory protein (G protein)-coupled receptors. The melatonin receptors are activated by the hormone melatonin (Mel), which is secreted by the pineal gland at night as part of the circadian clock. MEL-1A-R, a 37 kD protein, is thought to be involved in pacing the biological clock. However, both MEL-1A-R and MEL-1B-R are implicated in controlling cellular growth in response to melatonin. MEL-1B-R is an integral membrane protein expressed in retina and less in brain and hippocampus. Functional studies of NIH/3T3 cells stably expressing the MEL-1B-R melatonin receptor indicate that it is coupled to inhibition of adenylyl cyclase.Synonyms: MTNR1B, Melatonin receptor type 1B

    分子量

    approx. 40 kDa

    基因ID

    4544

    NCBI登录号

    NP_005950

    UniProt

    P49286
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