PAQR7 抗体
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北京 101111
Quick Overview for PAQR7 抗体 (ABIN317756)
抗原
See all PAQR7 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- MPRα antibody detects endogenous levels of mPRα protein.
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纯化方法
- Affinity chormatography
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应用备注
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ELISA: 1: 1000approx. 1: 5000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- PAQR7 (Progestin and AdipoQ Receptor Family Member VII (PAQR7))
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背景
- The steroid progesterone induces the resumption of maturation in oocytes via a nongenomic pathway through binding to a novel, membrane progestin receptor (mPR). This pathway inhibits adenylyl cyclase and reduces intracellular cAMP, and also activates mitogen-activated protein kinase to effect signal transduction pathways. Three distinct groups, designated α, β and γ, comprise this gene family. mPRα, also designated progestin and adipoQ receptor family member VII (PAQR7), consists of an extracellular N-terminus, an intracellular C-terminus, and seven transmembrane domains. It is expressed in ovary, testis, placenta, uterus and bladder. mPRβ, also designated progestin and adipoQ receptor family member VIII (PAQR8), consists of eight putative transmembrane regions and an intracellular N-terminus that contains a leucine-rich motif. It is a 354 amino acid protein with a molecular mass of about 40 kDa and is expressed in brain and spinal cord. Both mPRα and mPRβ may be G protein-coupled receptors and may be involved in oocyte maturation.Synonyms: Membrane progestin receptor alpha, Progestin and adipoQ receptor family member 7, Progestin and adipoQ receptor family member VII, mPR alpha
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分子量
- approx. 40 kDa
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基因ID
- 164091
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NCBI登录号
- NP_848509
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UniProt
- Q86WK9
抗原
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