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EDG4 抗体

LPAR2 适用: 人, 小鼠 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN317745
发货至: 中国
  • 抗原 See all EDG4 (LPAR2) 抗体
    EDG4 (LPAR2) (Lysophosphatidic Acid Receptor 2 (LPAR2))
    适用
    • 42
    • 25
    • 21
    • 1
    人, 小鼠
    宿主
    • 56
    • 1
    • 1
    克隆类型
    • 58
    多克隆
    标记
    • 26
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
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    This EDG4 antibody is un-conjugated
    应用范围
    • 25
    • 22
    • 15
    • 13
    • 13
    • 12
    • 11
    • 7
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    EDG-4 antibody detects endogenous levels of EDG-4 protein.(region surrounding Leu310)
    纯化方法
    Affinity-chromatography
    Top Product
    Discover our top product LPAR2 Primary Antibody
  • 应用备注
    ELISA: 1: 40000approx. 1: 60000. WB: 1: 500approx. 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1,0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    EDG4 (LPAR2) (Lysophosphatidic Acid Receptor 2 (LPAR2))
    别名
    EDG-4 / LPAR2 (LPAR2 产品)
    别名
    EDG-4 antibody, EDG4 antibody, LPA-2 antibody, LPA2 antibody, lpa2 antibody, Gpbar1 antibody, Edg4 antibody, IPA2 antibody, Pbx4 antibody, RGD1561336 antibody, zgc:101053 antibody, lysophosphatidic acid receptor 2 antibody, lysophosphatidic acid receptor 2 S homeolog antibody, G protein-coupled bile acid receptor 1 antibody, growth hormone releasing hormone receptor antibody, lysophosphatidic acid receptor 2a antibody, LPAR2 antibody, lpar2.S antibody, GPBAR1 antibody, Lpar2 antibody, GHRHR antibody, lpar2a antibody
    背景
    The EDG (endothelial differentiation gene) family of G protein coupled receptors consists of eight family members that bind lysophospholipid (LPL) mediators, including sphingosine-1-phosphate (SPP) and lysophosphatidic acid (LPA). EDG-1, EDG-3, EDG-5 (also designated H218 and AGR16) and EDG-8 bind SPP with high-affinity. EDG-6 is a low-affinity receptor for SPP. LPA preferentially binds to EDG-2, EDG-4 and EDG-7. The EDG receptors couple to multiple G proteins to signal through Ras, MAP kinase, Rho, Phospholipase C or other tyrosine kinases, which lead to cell survival, growth, migration and differentiation. EDG-1 signals through Gi proteins to activate Akt and is expressed in glioma cells. EDG-2 is expressed in brain, especially in white matter tract regions, while EDG-3 is expressed in cardiovascular tissue and in cerebellum. EDG-4 is highly expressed on leukocytes and brain, and EDG-5 has wide tissue distribution, including cardiovascular tissue and brain. Expressed in lymphoid and hematopoietic tissues and in lung, EDG-6 signals through Gi/o proteins, which activate growth related pathways.Synonyms: EDG4, Ipa-2, LPAR2, Lysophosphatidic acid receptor 2, Lysophosphatidic acid receptor Edg-4, endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor 4
    分子量
    approx. 39 kDa
    基因ID
    9170
    NCBI登录号
    NP_004711
    UniProt
    Q9HBW0
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