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CHRM5 抗体

CHRM5 适用: 人, 小鼠, 大鼠 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN317740
发货至: 中国
  • 抗原 See all CHRM5 抗体
    CHRM5 (Cholinergic Receptor, Muscarinic 5 (CHRM5))
    适用
    • 25
    • 11
    • 10
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 22
    • 3
    克隆类型
    • 24
    • 1
    多克隆
    标记
    • 14
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CHRM5 antibody is un-conjugated
    应用范围
    • 12
    • 9
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    MAChR M5 antibody detects endogenous levels of mAChR M5 protein.(region surrounding Pro224)
    交叉反应 (详细)
    Species reactivity (tested):Human, Mouse and Rat.
    纯化方法
    Affinity-chromatography
    Top Product
    Discover our top product CHRM5 Primary Antibody
  • 应用备注
    ELISA: 1: 5000approx. 1: 10000. WB: 1: 500approx. 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1,0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS) with 0.05 sodium azide, approx. pH 7.2.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    CHRM5 (Cholinergic Receptor, Muscarinic 5 (CHRM5))
    别名
    Muscarinic Acetylcholine Receptor M5 (CHRM5 产品)
    别名
    HM5 antibody, chrm5 antibody, wu:fd11g11 antibody, si:ch211-150c22.1 antibody, AChR-M5 antibody, M5R antibody, m5 antibody, CHKM5MR antibody, zgc:194865 antibody, zgc:194868 antibody, cholinergic receptor muscarinic 5 antibody, cholinergic receptor, muscarinic 5 antibody, cholinergic receptor, muscarinic 5b antibody, cholinergic receptor, muscarinic 5a antibody, CHRM5 antibody, Chrm5 antibody, chrm5b antibody, chrm5a antibody
    背景
    The muscarinic acetylcholine receptors (mAChR) mediate a variety of cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels. The mAChRs transducer signals by coupling to G-proteins, which then modulate several downstream effector proteins and ion channels. Five mAChR subtypes have been identified, designated M1 to M5. The five receptor subtypes show distinct patterns of tissue distribution, as well as distinct pharmacological and functional properties. The amino acid sequence of each mAChR subtype reflects a structure that is characteristic of G-protein coupled receptors, consisting of seven highly conserved transmembrane segments and a large intracellular region unique to each subtype, which constitutes the effector-coupling domain.Synonyms: CHRM5, mAChR M5, mAChR-M5
    分子量
    approx. 45 kDa
    基因ID
    1133
    NCBI登录号
    NP_036257
    UniProt
    P08912
    途径
    Synaptic Membrane
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