CHRM5 抗体
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北京 101111
Quick Overview for CHRM5 抗体 (ABIN317740)
抗原
See all CHRM5 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- MAChR M5 antibody detects endogenous levels of mAChR M5 protein.(region surrounding Pro224)
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交叉反应 （详细）
- Species reactivity (tested):Human, Mouse and Rat.
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纯化方法
- Affinity-chromatography
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anti-Cholinergic Receptor, Muscarinic 5 (CHRM5) (C-Term) antibody
CHRM5 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cholinergic Receptor, Muscarinic 5 (CHRM5) antibodyCHRM5 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 7E5H11 unconjugated
anti-Cholinergic Receptor, Muscarinic 5 (CHRM5) (AA 220-427) antibodyCHRM5 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cholinergic Receptor, Muscarinic 5 (CHRM5) (Cytoplasmic Domain) antibodyCHRM5 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cholinergic Receptor, Muscarinic 5 (CHRM5) (AA 230-430) antibodyCHRM5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Cholinergic Receptor, Muscarinic 5 (CHRM5) (AA 1-532) antibodyCHRM5 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Cholinergic Receptor, Muscarinic 5 (CHRM5) antibodyCHRM5 适用: 人, 小鼠 WB, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Cholinergic Receptor, Muscarinic 5 (CHRM5) (AA 281-330) antibodyCHRM5 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Cholinergic Receptor, Muscarinic 5 (CHRM5) (AA 7-24), (Extracellular) antibodyCHRM5 适用: 人 WB, FACS, LCI 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1: 5000approx. 1: 10000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS) with 0.05 sodium azide, approx. pH 7.2.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- CHRM5 (Cholinergic Receptor, Muscarinic 5 (CHRM5))
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别名
- Muscarinic Acetylcholine Receptor M5
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背景
- The muscarinic acetylcholine receptors (mAChR) mediate a variety of cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels. The mAChRs transducer signals by coupling to G-proteins, which then modulate several downstream effector proteins and ion channels. Five mAChR subtypes have been identified, designated M1 to M5. The five receptor subtypes show distinct patterns of tissue distribution, as well as distinct pharmacological and functional properties. The amino acid sequence of each mAChR subtype reflects a structure that is characteristic of G-protein coupled receptors, consisting of seven highly conserved transmembrane segments and a large intracellular region unique to each subtype, which constitutes the effector-coupling domain.Synonyms: CHRM5, mAChR M5, mAChR-M5
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分子量
- approx. 45 kDa
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基因ID
- 1133
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NCBI登录号
- NP_036257
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UniProt
- P08912
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途径
- Synaptic Membrane
抗原
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