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CasLTR2 抗体

This anti-CasLTR2 antibody is a 兔 多克隆 antibody detecting CasLTR2 in WB, IF 和 EIA. Suitable for 人.
产品编号 ABIN317732
发货至: 中国

Quick Overview for CasLTR2 抗体 (ABIN317732)

抗原

See all CasLTR2 (CYSLTR2) 抗体
CasLTR2 (CYSLTR2) (Cysteinyl Leukotriene Receptor 2 (CYSLTR2))

适用

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宿主

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克隆类型

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多克隆

标记

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This CasLTR2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
  • 特异性

    This antibody detects endogenous levels of CYSLTR2 protein(region surrrounding His324).

    交叉反应 (详细)

    Species reactivity (tested):Human.

    纯化方法

    Affinity-chromatography
  • 应用备注

    ELISA: 1: 40000approx. 1: 60000. WB: 1: 500approx. 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1,0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH 7.2, 0.05 % Sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    CasLTR2 (CYSLTR2) (Cysteinyl Leukotriene Receptor 2 (CYSLTR2))

    别名

    CYSLTR2

    背景

    Cysteinyl leukotriene (CysLTs) induce intracellular calcium mobilization through the binding of two distinct seven-transmembrane, G protein-coupled receptors, designated CysLT1 Receptor and CysLT2 Receptor, to induce potent bronchoconstriction. Airway smooth muscle and macrophages express both receptor types, and additionally monocytes and eosinophils express CysLT1 Receptor, while cardiac Purkinje cells, adrenal medulla, peripheral blood leukocytes and brain also utilize CysLT2 Receptor. The effects of the CysLT Receptors can be blocked by antagonists, indicating a therapeutic mechanism for the treatment of asthma and allergies.Synonyms: CYSLT2, CysLTR2, Cysteinyl leukotriene receptor 2, G-protein coupled receptor GPCR21, G-protein coupled receptor HG57, HG57, HPN321, hGPCR21

    分子量

    approx. 40 kDa

    基因ID

    57105

    NCBI登录号

    NP_065110

    UniProt

    Q9NS75
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