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IP6K2 抗体

IP6K2 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN317720
发货至: 中国
  • 抗原 See all IP6K2 抗体
    IP6K2 (Inositol Hexakisphosphate Kinase 2 (IP6K2))
    适用
    人, 小鼠, 大鼠
    宿主
    • 22
    • 4
    克隆类型
    • 24
    • 2
    多克隆
    标记
    • 19
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IP6K2 antibody is un-conjugated
    应用范围
    • 17
    • 12
    • 11
    • 6
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects endogenous levels of InsP6 kinase 2 / IP6K2 protein (region surrounding Leu188).
    交叉反应 (详细)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    纯化方法
    Affinity-chromatography
    Top Product
    Discover our top product IP6K2 Primary Antibody
  • 应用备注
    ELISA: 1: 40000approx. 1: 60000. WB: 1: 500approx. 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1,0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.2, 15 mM Sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    IP6K2 (Inositol Hexakisphosphate Kinase 2 (IP6K2))
    别名
    InsP6 Kinase 2 / IP6K2 (IP6K2 产品)
    别名
    IHPK2 antibody, ip6k2 antibody, ihpk2 antibody, cb1087 antibody, wu:fb47g07 antibody, wu:fi24d03 antibody, ihpk2b antibody, MGC69075 antibody, ihpk2a antibody, MGC84167 antibody, PIUS antibody, Ihpk2 antibody, Pius antibody, 1500005N04Rik antibody, AW050208 antibody, inositol hexakisphosphate kinase 2 antibody, inositol hexaphosphate kinase 2 antibody, inositol hexakisphosphate kinase 2a antibody, inositol hexaphosphate kinase 2 L homeolog antibody, inositol hexakisphosphate kinase 2b antibody, inositol hexaphosphate kinase 2 S homeolog antibody, IP6K2 antibody, ip6k2 antibody, ip6k2a antibody, ip6k2.L antibody, ip6k2b antibody, ip6k2.S antibody, MCYG_02913 antibody, Ip6k2 antibody
    背景
    The members of the inositol hexakisphosphate kinase family, IP6K1 and IP6K2, have a high affinity and selectivity for inositol hexakisphosphate (InsP6) as a substrate. IP6K1 and IP6K2 (also designated PiUS) convert InsP6 to PP-InsP5. However, neither kinase demonstrates any catalytic activity with other inositol pyrophosphates. The presence of InsP6, which inhibits serine/threonine protein phosphatases, increases the influx of calcium across the plasma membrane and implies that it may mediate the regulation of insulin exocytosis. IP6K1 was purified as a 54 kDa protein in rat brain extracts. By homology, IP6K1 and IP6K2 were characterized in mouse as a 50 kDa and 49 kDa protein, respectively. IP6K1 displays ATP synthase activity by transferring a phosphate from PP-InsP5 to ADP, which suggests a role for the IP6 kinases as high energy phosphate donors.Synonyms: IHPK2, Inositol hexakisphosphate kinase 2, P(i)-uptake stimulator, PiUS, TCCCIA00113
    分子量
    approx. 52 kDa
    基因ID
    51447
    NCBI登录号
    NP_001005909
    UniProt
    Q9UHH9
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