IP6K2 抗体
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Quick Overview for IP6K2 抗体 (ABIN317720)
抗原
See all IP6K2 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of InsP6 kinase 2 / IP6K2 protein (region surrounding Leu188).
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Affinity-chromatography
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anti-Inositol Hexakisphosphate Kinase 2 (IP6K2) (AA 1-180) antibody
IP6K2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Inositol Hexakisphosphate Kinase 2 (IP6K2) (Internal Region) antibodyIP6K2 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Inositol Hexakisphosphate Kinase 2 (IP6K2) antibodyIP6K2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Inositol Hexakisphosphate Kinase 2 (IP6K2) (AA 1-70) antibodyIP6K2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1C6 unconjugated
anti-Inositol Hexakisphosphate Kinase 2 (IP6K2) (AA 1-426) antibodyIP6K2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Inositol Hexakisphosphate Kinase 2 (IP6K2) (Center) antibodyIP6K2 适用: 人 WB, IHC, IF, IP, IC 宿主: 兔 Polyclonal unconjugated
anti-Inositol Hexakisphosphate Kinase 2 (IP6K2) (AA 226-258) antibodyIP6K2 适用: 小鼠 WB 宿主: 兔 Polyclonal RB53007 unconjugated
anti-Inositol Hexakisphosphate Kinase 2 (IP6K2) (Internal Region) antibodyIP6K2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Inositol Hexakisphosphate Kinase 2 (IP6K2) (AA 161-210) antibodyIP6K2 适用: 人, 小鼠, 大鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1: 40000approx. 1: 60000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2, 15 mM Sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- IP6K2 (Inositol Hexakisphosphate Kinase 2 (IP6K2))
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别名
- InsP6 Kinase 2 / IP6K2
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背景
- The members of the inositol hexakisphosphate kinase family, IP6K1 and IP6K2, have a high affinity and selectivity for inositol hexakisphosphate (InsP6) as a substrate. IP6K1 and IP6K2 (also designated PiUS) convert InsP6 to PP-InsP5. However, neither kinase demonstrates any catalytic activity with other inositol pyrophosphates. The presence of InsP6, which inhibits serine/threonine protein phosphatases, increases the influx of calcium across the plasma membrane and implies that it may mediate the regulation of insulin exocytosis. IP6K1 was purified as a 54 kDa protein in rat brain extracts. By homology, IP6K1 and IP6K2 were characterized in mouse as a 50 kDa and 49 kDa protein, respectively. IP6K1 displays ATP synthase activity by transferring a phosphate from PP-InsP5 to ADP, which suggests a role for the IP6 kinases as high energy phosphate donors.Synonyms: IHPK2, Inositol hexakisphosphate kinase 2, P(i)-uptake stimulator, PiUS, TCCCIA00113
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分子量
- approx. 52 kDa
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基因ID
- 51447
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NCBI登录号
- NP_001005909
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UniProt
- Q9UHH9
抗原
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