TACR3 抗体
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北京 101111
Quick Overview for TACR3 抗体 (ABIN317708)
抗原
See all TACR3 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of NK-3R protein.(region surrounding Pro343)
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纯化方法
- Affinity Chromatography using epitope-specific immunogen
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应用备注
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ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH ~7.2 containing 0.05 % Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- TACR3 (Tachykinin Receptor 3 (TACR3))
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背景
- Substance P (SP) and neurokinin-A (NK-A) are members of the tachykinins, and they function as modulators of the immune and hematopoietic systems. The tachykinins interact with each of three cloned neurokinin (NK) receptors (NK-1R, NK-2R, NK-3R), with SP and NK-A exhibiting binding preferences for NK-1R and NK-2R, respectively. NK-4R shares close homology with NK-3R, and both have nearly identical pharmacologicl properties. In the normal ileum and colon, NK-1R and NK-2R are localized to smooth muscle cells of the muscularis mucosae and propria and to a few inflammatory cells of the lamina propria. NK-1R expression is also found in the muscular wall of submucosal blood vessels, enteric neurons and, to a lesser degree, in surface epithelial cells. NK-3R is found in the spinal cord in both lamina X and lamina II.Synonyms: NK-3 receptor, NK-3R, NK3R, NKR, Neurokinin B receptor, Neuromedin-K receptor, TAC3R
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基因ID
- 6870
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NCBI登录号
- NP_001050
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UniProt
- P29371
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途径
- Feeding Behaviour
抗原
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