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Glucagon Receptor 抗体

GCGR 适用: 人, 大鼠, 小鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN317704
发货至: 中国
  • 抗原 See all Glucagon Receptor (GCGR) 抗体
    Glucagon Receptor (GCGR)
    适用
    • 56
    • 26
    • 25
    • 7
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    • 5
    • 4
    • 4
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    • 2
    • 2
    人, 大鼠, 小鼠
    宿主
    • 54
    • 1
    • 1
    克隆类型
    • 55
    • 1
    多克隆
    标记
    • 22
    • 6
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    • 2
    • 1
    • 1
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    • 1
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    • 1
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    This Glucagon Receptor antibody is un-conjugated
    应用范围
    • 41
    • 24
    • 18
    • 13
    • 13
    • 12
    • 7
    • 7
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    特异性
    This antibody detects endogenous levels of Glucagon Receptor protein.(region surrounding Lys136)
    交叉反应 (详细)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    纯化方法
    Affinity Chromatography using epitope-specific immunogen.
    Top Product
    Discover our top product GCGR Primary Antibody
  • 应用备注
    ELISA: 1/1000-1/10000. Western blot: 1/500-1/1000. Immunofluorescence: 1/50-1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS, pH ~7.2, 15 mM Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    Glucagon Receptor (GCGR)
    别名
    Glucagon Receptor (GCGR 产品)
    别名
    GCGR antibody, GGR antibody, GR antibody, glucagon receptor antibody, GCGR antibody, Gcgr antibody
    背景
    Glucagon, a pancreatic hormone, functions as an antagonist to insulin, stimulating the conversion of glycogen to glucose and increasing blood sugar levels. GLP-1 functions as a transmitter in the central nervous system, inhibiting feeding and drinking behavior. Both glucagon and GLP-1 function through their specific binding to the glucagon receptor or GLP-1R, respectively. The glucagon receptor shows expression in liver, kidney and adipose tissue. The 56 GLP-1R expression primarily localizes to areas of the hypothalamus involved in feeding behavior. Both receptors and their ligands serve as potential targets for the therapeutic treatment of diabetes.Synonyms: GCGR, GL-R
    分子量
    approx. 54 kDa
    基因ID
    2642
    NCBI登录号
    NP_000151
    UniProt
    P47871
    途径
    Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
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