Glucagon Receptor 抗体
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Quick Overview for Glucagon Receptor 抗体 (ABIN317704)
抗原
See all Glucagon Receptor (GCGR) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of Glucagon Receptor protein.(region surrounding Lys136)
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Affinity Chromatography using epitope-specific immunogen.
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anti-Glucagon Receptor (GCGR) (AA 11-110) antibody
GCGR 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Glucagon Receptor (GCGR) (AA 26-136) antibodyGCGR 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Glucagon Receptor (GCGR) (AA 1-140) antibodyGCGR 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Glucagon Receptor (GCGR) (Internal Region) antibodyGCGR 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glucagon Receptor (GCGR) (N-Term) antibodyGCGR 适用: 人, Cow, 猴, 犬, Hamster, 马 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Glucagon Receptor (GCGR) antibodyGCGR 适用: 人 IF, BR 宿主: 小鼠 Monoclonal hGR-2 F6 unconjugated Recombinant Antibody
anti-Glucagon Receptor (GCGR) (Extracellular Domain) antibodyGCGR 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Glucagon Receptor (GCGR) (N-Term) antibodyGCGR 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Glucagon Receptor (GCGR) (AA 200-212), (Extracellular) antibodyGCGR 适用: 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1/1000-1/10000. Western blot: 1/500-1/1000. Immunofluorescence: 1/50-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS, pH ~7.2, 15 mM Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Glucagon Receptor (GCGR)
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别名
- Glucagon Receptor
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背景
- Glucagon, a pancreatic hormone, functions as an antagonist to insulin, stimulating the conversion of glycogen to glucose and increasing blood sugar levels. GLP-1 functions as a transmitter in the central nervous system, inhibiting feeding and drinking behavior. Both glucagon and GLP-1 function through their specific binding to the glucagon receptor or GLP-1R, respectively. The glucagon receptor shows expression in liver, kidney and adipose tissue. The 56 GLP-1R expression primarily localizes to areas of the hypothalamus involved in feeding behavior. Both receptors and their ligands serve as potential targets for the therapeutic treatment of diabetes.Synonyms: GCGR, GL-R
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分子量
- approx. 54 kDa
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基因ID
- 2642
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NCBI登录号
- NP_000151
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UniProt
- P47871
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途径
- Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
抗原
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