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CysLTR1 抗体

The 兔 多克隆 anti-CysLTR1 antibody is suitable to detect CysLTR1 in samples from 人. It has been validated for WB, IF 和 EIA.
产品编号 ABIN317699
发货至: 中国
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Quick Overview for CysLTR1 抗体 (ABIN317699)

抗原

See all CysLTR1 (CYSLTR1) 抗体
CysLTR1 (CYSLTR1) (Cysteinyl Leukotriene Receptor 1 (CYSLTR1))

适用

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宿主

  • 40
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克隆类型

  • 41
多克隆

标记

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This CysLTR1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
  • 特异性

    This antibody detects endogenous levels of CYSLTR1 protein (region surrounding Lys172).

    交叉反应 (详细)

    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.

    纯化方法

    Affinity-chromatography using epitope-specific immunogen
  • 应用备注

    ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1,0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), 0.05 % Sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    CysLTR1 (CYSLTR1) (Cysteinyl Leukotriene Receptor 1 (CYSLTR1))

    别名

    CYSLTR1

    背景

    Cysteinyl leukotriene (CysLTs) induce intracellular calcium mobilization through the binding of two distinct seven-transmembrane, G protein-coupled receptors, designated CysLT1 and CysLT2 receptors, to induce potent broncoconstriction. Airway smooth muscle and macrophages express both receptor types, and additionally monocytes and eosinophils express CysLT1 receptor, while cardiac Purkinje cells, adrenal medulla, peripheral blood leukocytes and brain also utilize CysLT2 receptor. The effects of the CysLT receptors can be blocked by antagonists, indicating a therapeutic mechanism for the treatment of asthma and allergies.Synonyms: CysLTR1, Cysteinyl leukotriene D4 receptor, Cysteinyl leukotriene receptor 1, G-protein coupled receptor HG55, HG55, HMTMF81, LTD4 receptor

    分子量

    approx. 38 kDa

    基因ID

    10800

    NCBI登录号

    NP_006630

    UniProt

    Q9Y271
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