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PTH1R 抗体

PTH1R 适用: 人, 大鼠, 小鼠 WB, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN317698
发货至: 中国
  • 抗原 See all PTH1R 抗体
    PTH1R (Parathyroid Hormone 1 Receptor (PTH1R))
    适用
    • 42
    • 16
    • 11
    • 8
    • 8
    • 6
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 大鼠, 小鼠
    宿主
    • 34
    • 7
    • 1
    克隆类型
    • 35
    • 7
    多克隆
    标记
    • 31
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PTH1R antibody is un-conjugated
    应用范围
    • 28
    • 19
    • 16
    • 9
    • 8
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects endogenous levels of PTH/PTHrP-R protein.(region surrounding Leu187)
    交叉反应 (详细)
    Species reactivity (tested):Human, Mouse and Rat.
    纯化方法
    Affinity Chromatography using epitope-specific immunogen
    Top Product
    Discover our top product PTH1R Primary Antibody
  • 应用备注
    ELISA: 1/10000approx. 1/20000. Western Blot: 1/500approx. 1/1000. Immunohistochemistry: 1/50approx. 1/200. Immunofluorescence: 1/50approx. 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    PTH1R (Parathyroid Hormone 1 Receptor (PTH1R))
    别名
    PTH Receptor 1 (PTH1R 产品)
    别名
    PFE antibody, PTHR antibody, PTHR1 antibody, PPR antibody, Pthr antibody, Pthr1 antibody, pthr1 antibody, zPTH1R antibody, PTHrel antibody, PTH1 antibody, PTH antibody, parathyroid hormone 1 receptor antibody, parathyroid hormone 1 receptor a antibody, PTH1R antibody, Pth1r antibody, pth1ra antibody
    背景
    Parathyroid Hormone (PTH), which is also designated parathyrin, is an 84 amino acid single chain peptide that functions to regulate calcium metabolism by raising blood levels of calcium through various mechanisms. PTH stimulates bone formation to increase bone mass and strength in rats and humans. Within the PTH molecule, the essential activity is associated with the first 34 amino acids at the amino-terminus of the molecule. The gene encoding PTH maps to human chromosome 11p15.3-p15.1. Parathyroid hormone-related protein (PTH-rP) is an autocrine factor that is structurally related to PTH yet, unlike PTH, which is synthesized only by the parathyroid cells, PTH-rP is synthesized by several cell types. PTH-rP regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. Isolated from the culture medium of a human lung cancer cell line, PTH-rP produces PTH-like effects that are characterized as humoral hypercalcemia of malignancy.Synonyms: PTH/PTHrP type I receptor, PTH1R, PTHR, PTHR1, Parathyroid hormone 1 receptor, Parathyroid hormone/parathyroid hormone-related peptide receptor
    分子量
    approx. 52 kDa
    基因ID
    5745
    NCBI登录号
    NP_000307
    UniProt
    Q03431
    途径
    Regulation of Carbohydrate Metabolic Process
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