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CHRM1 抗体

CHRM1 适用: 大鼠, 人, 小鼠 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN317696
发货至: 中国
  • 抗原 See all CHRM1 抗体
    CHRM1 (Muscarinic Acetylcholine Receptor M1 (CHRM1))
    适用
    • 35
    • 32
    • 30
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    大鼠, 人, 小鼠
    宿主
    • 41
    • 2
    克隆类型
    • 43
    多克隆
    标记
    • 23
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CHRM1 antibody is un-conjugated
    应用范围
    • 39
    • 16
    • 8
    • 6
    • 5
    • 4
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects endogenous levels of Muscarinic acetylcholine receptor M1 / mAChR M1 protein (region surrounding Arg336).
    纯化方法
    Affinity-chromatography using epitope-specific immunogen
    Top Product
    Discover our top product CHRM1 Primary Antibody
  • 应用备注
    ELISA: 1: 5000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1,0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS) with 0.05 % Sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    CHRM1 (Muscarinic Acetylcholine Receptor M1 (CHRM1))
    别名
    Muscarinic Acetylcholine Receptor M1 (CHRM1 产品)
    别名
    M1 antibody, CHRM1 antibody, HM1 antibody, M1R antibody, mAChR antibody, Chrm-1 antibody, cholinergic receptor muscarinic 1 antibody, cholinergic receptor, muscarinic 1 antibody, cholinergic receptor, muscarinic 1, CNS antibody, CHRM1 antibody, Chrm1 antibody
    背景
    The muscarinic acetylcholine receptors (mAChR) mediate a variety of cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels. The mAChRs transducer signals by coupling to G-proteins, which then modulate several downstream effector proteins and ion channels. Five mAChR subtypes have been identified, designated M1 to M5. The five receptor subtypes show distinct patterns of tissue distribution, as well as distinct pharmacological and functional properties. The amino acid sequence of each mAChR subtype reflects a structure that is characteristic of G-protein coupled receptors, consisting of seven highly conserved transmembrane segments and a large intracellular region unique to each subtype, which constitutes the effector-coupling domain.Synonyms: CHRM1, mAChR M1, mAChR-M1
    分子量
    Approx. 50 kDa
    基因ID
    1128
    NCBI登录号
    NP_000729
    UniProt
    P11229
    途径
    Synaptic Membrane
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