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Adenosine A2b Receptor 抗体

This anti-Adenosine A2b Receptor antibody is a 兔 多克隆 antibody detecting Adenosine A2b Receptor in WB, IF 和 EIA. Suitable for 人.
产品编号 ABIN317695
发货至: 中国
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Quick Overview for Adenosine A2b Receptor 抗体 (ABIN317695)

抗原

See all Adenosine A2b Receptor (ADORA2B) 抗体
Adenosine A2b Receptor (ADORA2B)

适用

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宿主

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克隆类型

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多克隆

标记

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This Adenosine A2b Receptor antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
  • 特异性

    This antibody detects endogenous levels of Adenosine A2B-R protein.(region surrounding Trp270)

    纯化方法

    Affinity Chromatography using epitope-specific immunogen
  • 应用备注

    ELISA: 1/5000-1/20000. Western Blot: 1/500-1/1000. Immunofluorescence: 1/50-1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    Adenosine A2b Receptor (ADORA2B)

    别名

    Adenosine Receptor A2b

    背景

    Adenosine is involved in a variety of processes, including the synthesis of urea, the anti-inflammatory response, and the inhibition of protein synthesis. The adenosine receptors, including adenosine A1-R, adenosine A2A-R, adenosine A2B-R, and adenosine A3-R, are integral membrane proteins that are members of the G protein-coupled receptor family. The A1-R protein mediates ureagenesis in a partially calcium-dependent manner. Adenosine is known to mediate coronary vasodilation via the A2A-R receptor. Collagen synthasis and total protein synthesis are inhibited in certain cells by adenosine, acting via the A2B receptors. Activation of the A3-R receptor inhibits the induction of the cytokine TNFα and blocks the endotoxin CD14 receptor signal transduction pathway.Synonyms: ADORA2B

    分子量

    approx. 34 kDa

    基因ID

    136

    NCBI登录号

    NP_000667

    UniProt

    P29275

    途径

    cAMP Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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