Adenosine A2b Receptor 抗体
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- 抗原 See all Adenosine A2b Receptor (ADORA2B) 抗体
- Adenosine A2b Receptor (ADORA2B)
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Adenosine A2b Receptor antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
- 特异性
- This antibody detects endogenous levels of Adenosine A2B-R protein.(region surrounding Trp270)
- 纯化方法
- Affinity Chromatography using epitope-specific immunogen
- Top Product
- Discover our top product ADORA2B Primary Antibody
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- 应用备注
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ELISA: 1/5000-1/20000. Western Blot: 1/500-1/1000. Immunofluorescence: 1/50-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- Adenosine A2b Receptor (ADORA2B)
- 别名
- Adenosine Receptor A2b (ADORA2B 产品)
- 背景
- Adenosine is involved in a variety of processes, including the synthesis of urea, the anti-inflammatory response, and the inhibition of protein synthesis. The adenosine receptors, including adenosine A1-R, adenosine A2A-R, adenosine A2B-R, and adenosine A3-R, are integral membrane proteins that are members of the G protein-coupled receptor family. The A1-R protein mediates ureagenesis in a partially calcium-dependent manner. Adenosine is known to mediate coronary vasodilation via the A2A-R receptor. Collagen synthasis and total protein synthesis are inhibited in certain cells by adenosine, acting via the A2B receptors. Activation of the A3-R receptor inhibits the induction of the cytokine TNFα and blocks the endotoxin CD14 receptor signal transduction pathway.Synonyms: ADORA2B
- 分子量
- approx. 34 kDa
- 基因ID
- 136
- NCBI登录号
- NP_000667
- UniProt
- P29275
- 途径
- cAMP Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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