S1PR4 抗体
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北京 101111
Quick Overview for S1PR4 抗体 (ABIN317690)
抗原
See all S1PR4 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of EDG-6 protein.(region surrounding Ser368)
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纯化方法
- Affinity Chromatography using epitope-specific immunogen.
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anti-Sphingosine-1-Phosphate Receptor 4 (S1PR4) (AA 8-37), (N-Term) antibody
S1PR4 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB1829 unconjugated
anti-Sphingosine-1-Phosphate Receptor 4 (S1PR4) (Cytoplasmic Domain) antibodyS1PR4 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Receptor 4 (S1PR4) (AA 301-384) antibodyS1PR4 适用: 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Receptor 4 (S1PR4) (C-Term) antibodyS1PR4 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Receptor 4 (S1PR4) antibodyS1PR4 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Receptor 4 (S1PR4) (C-Term) antibodyS1PR4 适用: 人, 猴, 犬, Pig IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Receptor 4 (S1PR4) (Cytoplasmic Domain) antibodyS1PR4 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Receptor 4 (S1PR4) (AA 1-384) antibodyS1PR4 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Receptor 4 (S1PR4) (C-Term) antibodyS1PR4 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Receptor 4 (S1PR4) (C-Term) antibodyS1PR4 适用: 人 WB 宿主: 小鼠 Monoclonal 1 unconjugated
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应用备注
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ELISA: 1/20000approx. 1/40000. Western Blot: 1/500approx. 1/1000. Immunofluorescence: 1/50approx. 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH ~7.2 containing 0.05 % Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- S1PR4 (Sphingosine-1-Phosphate Receptor 4 (S1PR4))
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别名
- S1PR4 / EDG6
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背景
- The EDG (endothelial differentiation gene) family of G protein coupled receptors consists of eight family members that bind lysophospholipid (LPL) mediators, including sphingosine-1-phosphate (SPP) and lysophosphatidic acid (LPA). EDG-1, EDG-3, EDG-5 (also designated H218 and AGR16) and EDG-8 bind SPP with high affinity. EDG-6 is a low affinity receptor for SPP. LPA preferentially binds to EDG-2, EDG-4 and EDG-7. The EDG receptors couple to multiple G proteins to signal through Ras, MAP kinase, Rho, Phospholipase C or other tyrosine kinases, which lead to cell survival, growth, migration and differentiation. EDG-1 signals through Gi proteins to activate Akt and is expressed in glioma cells. EDG-2 is expressed in brain, especially in white matter tract regions, while EDG-3 is expressed in cardiovascular tissue and in cerebellum. EDG-4 is highly expressed on leukocytes and brain, and EDG-5 has wide tissue distribution, including cardiovascular tissue and brain.Synonyms: EDG-6, Endothelial differentiation G-protein coupled receptor 6, S1P receptor Edg-6, Sphingosine 1-phosphate receptor 4, Sphingosine 1-phosphate receptor Edg-6
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分子量
- approx. 40 kDa
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基因ID
- 8698
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NCBI登录号
- NP_003766
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UniProt
- O95977
抗原
-
