EDG4 抗体
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北京 101111
Quick Overview for EDG4 抗体 (ABIN317689)
抗原
See all EDG4 (LPAR2) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of EDG-4 protein (region surrounding Gln330).
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纯化方法
- Affinity-chromatography using epitope-specific immunogen
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anti-Lysophosphatidic Acid Receptor 2 (LPAR2) (Cytoplasmic Domain) antibody
LPAR2 适用: 人 IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Lysophosphatidic Acid Receptor 2 (LPAR2) (AA 3-32), (N-Term) antibodyLPAR2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB1827 unconjugated
anti-Lysophosphatidic Acid Receptor 2 (LPAR2) (AA 1-100) antibodyLPAR2 适用: 小鼠, 大鼠 ELISA, IF (p), FACS, IHC (p), IF (cc), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Lysophosphatidic Acid Receptor 2 (LPAR2) (AA 8-27) antibodyLPAR2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Lysophosphatidic Acid Receptor 2 (LPAR2) antibodyLPAR2 适用: 人, 小鼠, 大鼠 IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Lysophosphatidic Acid Receptor 2 (LPAR2) (AA 250-350) antibodyLPAR2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Lysophosphatidic Acid Receptor 2 (LPAR2) (C-Term) antibodyLPAR2 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lysophosphatidic Acid Receptor 2 (LPAR2) antibodyLPAR2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Lysophosphatidic Acid Receptor 2 (LPAR2) (AA 271-320) antibodyLPAR2 适用: 人, 小鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Lysophosphatidic Acid Receptor 2 (LPAR2) (AA 290-339) antibodyLPAR2 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2, 0.05 % Sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- EDG4 (LPAR2) (Lysophosphatidic Acid Receptor 2 (LPAR2))
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别名
- EDG-4 / LPAR2
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背景
- The EDG (endothelial differentiation gene) family of G protein coupled receptors consists of eight family members that bind lysophospholipid (LPL) mediators, including sphingosine-1-phosphate (SPP) and lysophosphatidic acid (LPA). EDG-1, EDG-3, EDG-5 (also designated H218 and AGR16) and EDG-8 bind SPP with high-affinity. EDG-6 is a low-affinity receptor for SPP. LPA preferentially binds to EDG-2, EDG-4 and EDG-7. The EDG receptors couple to multiple G proteins to signal through Ras, MAP kinase, Rho, Phospholipase C or other tyrosine kinases, which lead to cell survival, growth, migration and differentiation. EDG-1 signals through Gi proteins to activate Akt and is expressed in glioma cells. EDG-2 is expressed in brain, especially in white matter tract regions, while EDG-3 is expressed in cardiovascular tissue and in cerebellum. EDG-4 is highly expressed on leukocytes and brain, and EDG-5 has wide tissue distribution, including cardiovascular tissue and brain. Expressed in lymphoid and hematopoietic tissues and in lung, EDG-6 signals through Gi/o proteins, which activate growth related pathways.Synonyms: EDG4, Ipa-2, LPAR2, Lysophosphatidic acid receptor 2, Lysophosphatidic acid receptor Edg-4, endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor 4
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分子量
- approx. 39 kDa
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基因ID
- 9170
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NCBI登录号
- NP_004711
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UniProt
- Q9HBW0
抗原
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