MCHR2 抗体
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Quick Overview for MCHR2 抗体 (ABIN317652)
抗原
See all MCHR2 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of MCH-2R protein.(region surrounding Met332)
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纯化方法
- Affinity Chromatography using epitope-specific immunogen.
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anti-Melanin-Concentrating Hormone Receptor 2 (MCHR2) (AA 1-39) antibody
MCHR2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Melanin-Concentrating Hormone Receptor 2 (MCHR2) (Cytoplasmic Domain) antibodyMCHR2 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Melanin-Concentrating Hormone Receptor 2 (MCHR2) (C-Term) antibodyMCHR2 适用: 人 ELISA, WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1/1000-1/5000. Western Blot: 1/500-1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH ~7.2 containing 0,05 % Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- MCHR2 (Melanin-Concentrating Hormone Receptor 2 (MCHR2))
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别名
- MCHR2 / GPR145
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背景
- Melanin-concentrating hormone (MCH) is a 19 amino acid cyclic neuropeptide,which is mainly expressed in the hypothalamus. MCH modulates feeding behavior, aggression, anxiety, arousal and reproductive function in mammals by controlling the release of luteinizing hormone (LH). The melanin-concentrating hormone receptor (MCHR, also designated SLC-1) is a glycosylated G-protein coupled receptor that migrates between 45-50 kDa on SDS-PAGE. MCHR mediates the effects of MCH through Gai and/or Gaq signaling and is expressed in several regions of the brain, including the cerebral cortex, amygdala, thalamus and hypothalamus. MCH and MCHR have also been implicated in stimulating leptin expression and secretion in adipocytes, which suggests that the melanin-concentrating hormone and its receptor may be potential targets for modulating obesity.Synonyms: G-protein coupled receptor 145, GPRv17, MCH receptor 2, MCH-2R, MCH-R2, MCHR-2, Melanin-concentrating hormone receptor 2, SLT
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分子量
- approx. 39 kDa
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基因ID
- 84539
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NCBI登录号
- NP_001035269
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UniProt
- Q969V1
抗原
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