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MCHR2 抗体

MCHR2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN317652
发货至: 中国
  • 抗原 See all MCHR2 抗体
    MCHR2 (Melanin-Concentrating Hormone Receptor 2 (MCHR2))
    适用
    • 30
    • 2
    • 1
    • 1
    • 1
    宿主
    • 29
    • 1
    克隆类型
    • 30
    多克隆
    标记
    • 17
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MCHR2 antibody is un-conjugated
    应用范围
    • 14
    • 8
    • 5
    • 4
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    特异性
    This antibody detects endogenous levels of MCH-2R protein.(region surrounding Met332)
    纯化方法
    Affinity Chromatography using epitope-specific immunogen.
    Top Product
    Discover our top product MCHR2 Primary Antibody
  • 应用备注
    ELISA: 1/1000-1/5000. Western Blot: 1/500-1/1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH ~7.2 containing 0,05 % Sodium Azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    MCHR2 (Melanin-Concentrating Hormone Receptor 2 (MCHR2))
    别名
    MCHR2 / GPR145 (MCHR2 产品)
    别名
    GPR145 antibody, GPRv17 antibody, MCH-2R antibody, MCH-R2 antibody, MCH2 antibody, MCH2R antibody, MCHR-2 antibody, SLT antibody, melanin concentrating hormone receptor 2 antibody, MCHR2 antibody
    背景
    Melanin-concentrating hormone (MCH) is a 19 amino acid cyclic neuropeptide,which is mainly expressed in the hypothalamus. MCH modulates feeding behavior, aggression, anxiety, arousal and reproductive function in mammals by controlling the release of luteinizing hormone (LH). The melanin-concentrating hormone receptor (MCHR, also designated SLC-1) is a glycosylated G-protein coupled receptor that migrates between 45-50 kDa on SDS-PAGE. MCHR mediates the effects of MCH through Gai and/or Gaq signaling and is expressed in several regions of the brain, including the cerebral cortex, amygdala, thalamus and hypothalamus. MCH and MCHR have also been implicated in stimulating leptin expression and secretion in adipocytes, which suggests that the melanin-concentrating hormone and its receptor may be potential targets for modulating obesity.Synonyms: G-protein coupled receptor 145, GPRv17, MCH receptor 2, MCH-2R, MCH-R2, MCHR-2, Melanin-concentrating hormone receptor 2, SLT
    分子量
    approx. 39 kDa
    基因ID
    84539
    NCBI登录号
    NP_001035269
    UniProt
    Q969V1
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