G Protein-Coupled Receptor 119 抗体
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Quick Overview for G Protein-Coupled Receptor 119 抗体 (ABIN317642)
抗原
See all G Protein-Coupled Receptor 119 (GPR119) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of GPR119 protein.(region surrounding Val227)
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纯化方法
- Affinity Chromatography using epitope-specific immunogen.
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anti-G Protein-Coupled Receptor 119 (GPR119) (Cytoplasmic Domain) antibody
GPR119 适用: 人, Bat IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 119 (GPR119) antibodyGPR119 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 119 (GPR119) (Cytoplasmic Domain) antibodyGPR119 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 119 (GPR119) (Internal Region) antibodyGPR119 适用: 人, 小鼠 WB, ELISA, IF, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 119 (GPR119) (Internal Region) antibodyGPR119 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 119 (GPR119) (Center) antibodyGPR119 适用: 人, 猴 WB, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 119 (GPR119) antibodyGPR119 适用: 人, 小鼠, 大鼠, 犬 ELISA, IF, BP 宿主: 兔 Chimeric Gipg013 unconjugated Recombinant Antibody
anti-G Protein-Coupled Receptor 119 (GPR119) (C-Term) antibodyVerified GPR119 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 119 (GPR119) (AA 186-235) antibodyGPR119 适用: 人 WB, ELISA, IF, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 119 (GPR119) (AA 186-235) antibodyGPR119 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1/1000-1/5000. Western Blot: 1/500-1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH ~7.2 containing 0,05 % Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- G Protein-Coupled Receptor 119 (GPR119)
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别名
- GPR119
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背景
- G protein-coupled receptors (GPRs) are a protein family of transmembrane receptors that transmit an extracellular signal (ligand binding) into an intra cellular signal (G protein activation). GPR signaling is an evolutionarily ancient mechanism used by all eukaryotes to sense environmental stimuli and mediate cell-cell communication. All of the receptors have seven membrane- spanning domains and the extracellular parts of the receptor can be glycosylated. These extracellular loops also contain two highly conserved cysteine residues which create disulfide bonds to stabilize the receptor structure. GPR119 is a 335 amino acid protein that is mainly expressed in the pancreas. It is an endogenous receptor for lysophosphatidylcholine (LPC), which is is a lipid mediator involved in insulin secretion from pancreatic cells. GPR119 may participate in this insulin secretion, suggesting that it may be potential target for new anti-diabetic drugs.Synonyms: G-protein coupled receptor 119, Glucose-dependent insulinotropic receptor
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分子量
- approx. 37 kDa
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基因ID
- 139760
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NCBI登录号
- NP_848566
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UniProt
- Q8TDV5
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途径
- Hormone Transport, Peptide Hormone Metabolism
抗原
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