beta 2 Adrenergic Receptor 抗体
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Quick Overview for beta 2 Adrenergic Receptor 抗体 (ABIN317627)
抗原
See all beta 2 Adrenergic Receptor (ADRB2) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of AR-beta2 protein.(region surrounding Cys378)
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纯化方法
- Affinity Chromatography using epitope-specific immunogen.
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应用备注
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ELISA: 1/5000-1/20000. Western Blot: 1/500-1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH ~7.2 containing 0,05 % Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- beta 2 Adrenergic Receptor (ADRB2) (Adrenergic, beta-2-, Receptor, Surface (ADRB2))
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别名
- beta-2 Adrenergic Receptor
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背景
- Adrenergic receptors (ARs) (the term ?adrenergic? reflects the alternative name for epinephrine, adrenaline) include four general types (alpha1, alpha2, beta1 and beta2) which are found in different target tissues and differ in their affinities and responses to various agonists and antagonists. cDNA clones have been isolated for all of the major AR subtypes and a number of closely related receptors have been identified by this approach. Each of the receptors have been shown to consist of single polypeptide chains which transverse the plasma membrane seven times, presumably forming a bundle of helices within the membrane. These transmembrane regions are hydrophobic and are interconnected by extracellular and intracellular hydrophilic loops. The coupling of ARs to specific intracellular effectors is mediated through diverse heterotrimeric G proteins and is regulated by G protein-coupled receptor kinases (GRKs), cAMP-dependent protein kinase A and protein kinase C directed phosphorylation.Synonyms: ADRB2, ADRB2R, B2AR, Beta-2 adrenoreceptor
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基因ID
- 9606
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UniProt
- P07550
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途径
- cAMP Metabolic Process, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Brown Fat Cell Differentiation
抗原
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