RPL10 抗体
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北京 101111
Quick Overview for RPL10 抗体 (ABIN317605)
抗原
See all RPL10 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of QM protein.(region surrounding Phe34)
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纯化方法
- Affinity Chromatography using epitope-specific immunogen.
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应用备注
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Western Blot: 1/500-1/1000. ELISA: 1/20000-1/40000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH ~7.2 containing 0.05 % Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- RPL10 (Ribosomal Protein L10 (RPL10))
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别名
- RPL10
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背景
- The c-Jun protein is a major component of the transcription factor AP-1, originally shown to mediate phorbol ester tumor promoter (TPA)-induced expression of responsive genes through the TPA-response element (TRE). The Jun proteins form homo- and heterodimers which bind the TRE, while Fos proteins are active only as heterodimers with any of the Jun proteins. Fos/Jun heterodimers have a much higher affinity for the TRE than Jun homodimers. A distant member of the MAP kinase family, designated c-Jun NH2-terminal kinase (JNK1) functions to regulate c-Jun by phosphorylation at the amino terminal serine regulatory sites, Ser 63 and Ser 73). QM has been described as a transcription factor that can function to bind DNA directly or alternatively can interact with c-Jun to inhibit transactivation of AP-1 promoter driven reporter vectors by Jun-Jun homodimers. QM is highly conserved throughout eukaryotic evolution and is apparently a member of a multi-gene family.Synonyms: 60S ribosomal protein L10, DXS648E, Laminin receptor homolog, QM, Tumor suppressor QM
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基因ID
- 6134
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NCBI登录号
- NP_006004
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UniProt
- P27635
抗原
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