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SNCA 抗体 (AA 119-140)

The 小鼠 单克隆 anti-SNCA antibody (Clone 3B6) (ABIN317562) specifically detects SNCA in WB 和 EIA. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN317562
发货至: 中国
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Quick Overview for SNCA 抗体 (AA 119-140) (ABIN317562)

抗原

See all SNCA 抗体
SNCA (Synuclein, alpha (SNCA))

适用

  • 327
  • 191
  • 165
  • 14
  • 11
  • 10
  • 10
  • 7
  • 7
  • 5
  • 2
  • 2
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 238
  • 108
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
小鼠

克隆类型

  • 180
  • 179
单克隆

标记

  • 164
  • 25
  • 18
  • 11
  • 10
  • 9
  • 9
  • 9
  • 9
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  • 2
  • 2
  • 2
  • 2
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  • 2
This SNCA antibody is un-conjugated

应用范围

  • 272
  • 164
  • 160
  • 120
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  • 51
  • 36
  • 29
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  • 22
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  • 5
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Enzyme Immunoassay (EIA)

克隆位点

3B6
  • 抗原表位

    • 75
    • 24
    • 17
    • 16
    • 14
    • 13
    • 10
    • 10
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 119-140

    特异性

    The antibody recognizes α,β - Synuclein.

    产品特性

    Synonyms: NACP, PARK1, Non-A beta component of AD amyloid, Non-A4 component of amyloidprecursor

    纯化方法

    Protein-G affinity chromatography

    免疫原

    Recombinant human α-synuclein (119-140aa) purified from E. coli

    亚型

    IgG1
  • 应用备注

    ELISA. Western blot (1: 1,000 - 1: 2,000).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.0 mg/mL

    缓冲液

    PBS, pH 7.4, containing 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    SNCA (Synuclein, alpha (SNCA))

    别名

    alpha-Synuclein / SNCA

    背景

    α-synuclein (amino acids 119-140), an acidic neuronal protein of 140 amino acids, is extremely heat-resistant and is natively unfolded with an extended structure primarily composed of random coils. α-synuclein has been suggested to be implicated in the pathogenesis of Parkinson's disease and related neurodegenerative disorders, and more recently, to be an important regulatory component of vesicular transport in neuronal cells. Specially, the non-Aβ component of amyloid plaques is a highly amyloidogenic peptide consisting of 35 amino acids which was first identified associated with senile plaques in the Alzheimer's disease brain.Synonyms: NACP, Non-A beta component of AD amyloid, Non-A4 component of amyloid precursor, PARK1

    基因ID

    6622

    UniProt

    P37840

    途径

    Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity
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