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IL-33 抗体 (AA 112-270)

This 小鼠 单克隆 anti-IL-33 antibody (Clone 4-00E-009) specifically detects IL-33 in WB 和 EIA. The antibody is reactive with 人 samples.
产品编号 ABIN317536
发货至: 中国
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Quick Overview for IL-33 抗体 (AA 112-270) (ABIN317536)

抗原

See all IL-33 (IL33) 抗体
IL-33 (IL33) (Interleukin 33 (IL33))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This IL-33 antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)

克隆位点

4-00E-009
  • 抗原表位

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    AA 112-270

    特异性

    The antibody recognizes human IL-33. Other species not tested.

    产品特性

    Synonyms: IL-33, IL1F11, IL-1F11, NFHEV, NF-HEV, C9orf26, Interleukin-1 family member 11, Nuclear factorfrom high endothelial venules

    纯化方法

    Protein-G affinity chromatography

    免疫原

    Recombinant human IL-33 (112-270 aa) purified from E. coli

    亚型

    IgG2b
  • 应用备注

    ELISA. Western blot (1: 500 - 1: 2,000).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.0 mg/mL

    缓冲液

    PBS, pH 7.4, containing 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    IL-33 (IL33) (Interleukin 33 (IL33))

    别名

    Interleukin-33 (IL33)

    背景

    Interleukin 33 (IL-33) is a 32 kDa proinflammatory cytokine and intracellular nuclear factor with transcriptional regulatory properties. IL-33 is structurally related to IL-1, which induces helper T-cells to produce type 2 cytokines and acts through the receptor IL1RL-1 (IL1 receptor-like-1), which is known also as ST2. Binding of IL-33 to this receptor activates NF-kappa-B and MAP kinases and induces in vitro Th2 cells to produce cytokines. In vivo, IL-33 induces expression of IL-4, IL-5, IL-13 and leads to severe pathological changes in mucosal organs and in vitro, it can be divided to N-terminal fragment of 12 kDa and C-terminal fragment of 18 kDa by cleavage of caspase-1.Synonyms: C9orf26, IL-1F11, IL-33, IL1F11, Interleukin-1 family member 11, NF-HEV, NFHEV, Nuclear factor from high endothelial venules

    基因ID

    90865

    UniProt

    O95760

    途径

    Production of Molecular Mediator of Immune Response
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