Cathepsin L 抗体 (AA 114-333)
Quick Overview for Cathepsin L 抗体 (AA 114-333) (ABIN317508)
抗原
See all Cathepsin L (CTSL1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
 - AA 114-333
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特异性
 - The antibody recognizes Human Cathepsin L. Other species not tested.
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产品特性
 - Synonyms: CTSL1, CTSL, MEP, Cathepsin-L1, Major excreted protein
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纯化方法
 - Protein-G affinity chromatography
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免疫原
 - Recombinant Human Cathepsin L (114-333 aa) purified from E. coli
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亚型
 - IgG2b
 
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应用备注
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                        ELISA. Western blot: 1/1000-1/2000. Immunohistochemistry on Paraffin Sections: 5 μg/mL. 
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 
                                            
限制
 - 仅限研究用
 
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状态
 - Liquid
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浓度
 - 1.0 mg/mL
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缓冲液
 - PBS, pH 7.4, containing 0.09 % Sodium Azide
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储存液
 - Sodium azide
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注意事项
 - This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
 - 4 °C/-20 °C
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储存方法
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                        Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. - 
                                            
有效期
 - 12 months
 
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                                            : "Cathepsin L inhibition suppresses drug resistance in vitro and in vivo: a putative mechanism."    in: American journal of physiology. Cell physiology, Vol. 296, Issue 1, pp. C65-74, (2009)         (PubMed).        
 
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                                            : "Cathepsin L inhibition suppresses drug resistance in vitro and in vivo: a putative mechanism."    in: American journal of physiology. Cell physiology, Vol. 296, Issue 1, pp. C65-74, (2009)         (PubMed).        
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- Cathepsin L (CTSL1) (Cathepsin L1 (CTSL1))
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别名
 - Cathepsin L1
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背景
 - Cathepsin L, a lysosomal endopeptidase expressed in most eukaryotic cells, is a member of the papain-like family of cysteine proteinases. Cathepsin L can be induced by many different signaling events, including growth factor, secondary messenger and tumor promoters. Cathepsin L is translated as pre-procathepsin L, transferred through the Golgi apparatus as procathepsin L and then stored in lysosomes as mature cathepsin L.Synonyms: CTSL, CTSL1, Cathepsin-L1, MEP, Major excreted protein
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基因ID
 - 1514
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UniProt
 - P07711
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途径
 - Activation of Innate immune Response, Toll-Like Receptors Cascades
 
抗原
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