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Cathepsin L 抗体 (AA 114-333)

Cited in 1 publication. This anti-Cathepsin L antibody is a 小鼠 单克隆 antibody detecting Cathepsin L in WB, IHC (p) 和 EIA. Suitable for 人.
产品编号 ABIN317508
发货至: 中国
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Quick Overview for Cathepsin L 抗体 (AA 114-333) (ABIN317508)

抗原

See all Cathepsin L (CTSL1) 抗体
Cathepsin L (CTSL1) (Cathepsin L1 (CTSL1))

适用

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宿主

  • 86
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小鼠

克隆类型

  • 86
  • 20
单克隆

标记

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This Cathepsin L antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

克隆位点

2H7
  • 抗原表位

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    AA 114-333

    特异性

    The antibody recognizes Human Cathepsin L. Other species not tested.

    产品特性

    Synonyms: CTSL1, CTSL, MEP, Cathepsin-L1, Major excreted protein

    纯化方法

    Protein-G affinity chromatography

    免疫原

    Recombinant Human Cathepsin L (114-333 aa) purified from E. coli

    亚型

    IgG2b
  • 应用备注

    ELISA. Western blot: 1/1000-1/2000. Immunohistochemistry on Paraffin Sections: 5 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.0 mg/mL

    缓冲液

    PBS, pH 7.4, containing 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.

    有效期

    12 months
  • Zheng, Chu, Chou, Gallati, Dier, Mirkin, Mousa, Rebbaa: "Cathepsin L inhibition suppresses drug resistance in vitro and in vivo: a putative mechanism." in: American journal of physiology. Cell physiology, Vol. 296, Issue 1, pp. C65-74, (2009) (PubMed).

  • 抗原

    Cathepsin L (CTSL1) (Cathepsin L1 (CTSL1))

    别名

    Cathepsin L1

    背景

    Cathepsin L, a lysosomal endopeptidase expressed in most eukaryotic cells, is a member of the papain-like family of cysteine proteinases. Cathepsin L can be induced by many different signaling events, including growth factor, secondary messenger and tumor promoters. Cathepsin L is translated as pre-procathepsin L, transferred through the Golgi apparatus as procathepsin L and then stored in lysosomes as mature cathepsin L.Synonyms: CTSL, CTSL1, Cathepsin-L1, MEP, Major excreted protein

    基因ID

    1514

    UniProt

    P07711

    途径

    Activation of Innate immune Response, Toll-Like Receptors Cascades
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