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Sialoadhesin/CD169 抗体 (FITC)

SIGLEC1 适用: 小鼠 FACS 宿主: 大鼠 Monoclonal 3D6-112 FITC
产品编号 ABIN317444
发货至: 中国
  • 抗原 See all Sialoadhesin/CD169 (SIGLEC1) 抗体
    Sialoadhesin/CD169 (SIGLEC1) (Sialic Acid Binding Ig-Like Lectin 1, Sialoadhesin (SIGLEC1))
    适用
    • 46
    • 21
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    小鼠
    宿主
    • 36
    • 17
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    大鼠
    克隆类型
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    单克隆
    标记
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    This Sialoadhesin/CD169 antibody is conjugated to FITC
    应用范围
    • 44
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    Flow Cytometry (FACS)
    特异性
    This antibody recognizes Mouse CD169, a sialic acid binding site of sialoadhesin.
    交叉反应 (详细)
    Species reactivity (tested):Mouse.
    产品特性
    Synonyms: Sialoadhesin, Siglec-1, Sialic acid-binding Ig-like lectin 1
    纯化方法
    Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
    免疫原
    Purified Sialoadhesin. Spleen cells from an immunised AO rat were fused with the cells of the Y3 rat myeloma cellline.
    克隆位点
    3D6-112
    亚型
    IgG2a
    Top Product
    Discover our top product SIGLEC1 Primary Antibody
  • 应用备注
    Flow Cytometry: neat-1/5 (The Fc region of monoclonal antibodies may bindnon-specifically to cells expressing low affinity Fc receptors).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.1 mg/mL
    缓冲液
    PBS, 0.09 % Sodium Azide, 1 % BSA
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.
    有效期
    12 months
  • 抗原
    Sialoadhesin/CD169 (SIGLEC1) (Sialic Acid Binding Ig-Like Lectin 1, Sialoadhesin (SIGLEC1))
    别名
    CD169 / SIGLEC1 (SIGLEC1 产品)
    别名
    Cd169 antibody, Siglec-1 antibody, Sn antibody, CD169 antibody, SIGLEC-1 antibody, SN antibody, dJ1009E24.1 antibody, SA antibody, SIGLEC1 antibody, p210 antibody, pSn antibody, sialic acid binding Ig like lectin 1 antibody, sialic acid binding Ig-like lectin 1, sialoadhesin antibody, SIGLEC1 antibody, Siglec1 antibody
    背景
    Two families of mammalian lectin like adhesion molecules have been shown to bind glycoconjugate ligands in a sialic acid dependent manner: the selectins and the sialoadhesins. The sialoadhesin family has 4 members: CD22, a B cell specific marker, myelin associated glycoprotein (MAG), which is expressed on oligodendrocytes and Schwann cells, CD33, a myeloid differentiation antigen, and sialoadhesin, which is expressed only by a subpopulation of tissue macrophages. Involved in cell-cell interactions, sialoadhesin is structurally related to the 3 other listed members of the sialoadhesin family. CD169 is a sialic acid binding site of sialoadhesin. CD169 is a macrophage receptor expressed on stromal macrophages in many tissues, particularly found in lymph nodes, bone marrow and spleen.Synonyms: Sialic acid-binding Ig-like lectin 1, Sialoadhesin, Siglec-1
    基因ID
    20612
    UniProt
    Q62230
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