Sialoadhesin/CD169 抗体 (FITC)
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- 抗原 See all Sialoadhesin/CD169 (SIGLEC1) 抗体
- Sialoadhesin/CD169 (SIGLEC1) (Sialic Acid Binding Ig-Like Lectin 1, Sialoadhesin (SIGLEC1))
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适用
- 小鼠
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宿主
- 大鼠
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克隆类型
- 单克隆
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标记
- This Sialoadhesin/CD169 antibody is conjugated to FITC
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应用范围
- Flow Cytometry (FACS)
- 特异性
- This antibody recognizes Mouse CD169, a sialic acid binding site of sialoadhesin.
- 交叉反应 (详细)
- Species reactivity (tested):Mouse.
- 产品特性
- Synonyms: Sialoadhesin, Siglec-1, Sialic acid-binding Ig-like lectin 1
- 纯化方法
- Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
- 免疫原
- Purified Sialoadhesin. Spleen cells from an immunised AO rat were fused with the cells of the Y3 rat myeloma cellline.
- 克隆位点
- 3D6-112
- 亚型
- IgG2a
- Top Product
- Discover our top product SIGLEC1 Primary Antibody
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- 应用备注
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Flow Cytometry: neat-1/5 (The Fc region of monoclonal antibodies may bindnon-specifically to cells expressing low affinity Fc receptors).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 0.1 mg/mL
- 缓冲液
- PBS, 0.09 % Sodium Azide, 1 % BSA
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. - 有效期
- 12 months
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- 抗原
- Sialoadhesin/CD169 (SIGLEC1) (Sialic Acid Binding Ig-Like Lectin 1, Sialoadhesin (SIGLEC1))
- 别名
- CD169 / SIGLEC1 (SIGLEC1 产品)
- 背景
- Two families of mammalian lectin like adhesion molecules have been shown to bind glycoconjugate ligands in a sialic acid dependent manner: the selectins and the sialoadhesins. The sialoadhesin family has 4 members: CD22, a B cell specific marker, myelin associated glycoprotein (MAG), which is expressed on oligodendrocytes and Schwann cells, CD33, a myeloid differentiation antigen, and sialoadhesin, which is expressed only by a subpopulation of tissue macrophages. Involved in cell-cell interactions, sialoadhesin is structurally related to the 3 other listed members of the sialoadhesin family. CD169 is a sialic acid binding site of sialoadhesin. CD169 is a macrophage receptor expressed on stromal macrophages in many tissues, particularly found in lymph nodes, bone marrow and spleen.Synonyms: Sialic acid-binding Ig-like lectin 1, Sialoadhesin, Siglec-1
- 基因ID
- 20612
- UniProt
- Q62230
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