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Sialoadhesin/CD169 抗体 (FITC)

SIGLEC1 适用: Pig FACS 宿主: 小鼠 Monoclonal 3B1-11 FITC
产品编号 ABIN317425
发货至: 中国
  • 抗原 See all Sialoadhesin/CD169 (SIGLEC1) 抗体
    Sialoadhesin/CD169 (SIGLEC1) (Sialic Acid Binding Ig-Like Lectin 1, Sialoadhesin (SIGLEC1))
    适用
    • 46
    • 21
    • 20
    • 4
    • 3
    Pig
    宿主
    • 36
    • 17
    • 16
    • 4
    小鼠
    克隆类型
    • 38
    • 32
    • 1
    单克隆
    标记
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    This Sialoadhesin/CD169 antibody is conjugated to FITC
    应用范围
    • 44
    • 28
    • 22
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    • 11
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    Flow Cytometry (FACS)
    特异性
    This antibody is specific for the CD169 cell surface antigen, also known as sialoadhesin, which is expressed by subsets of cells of the macrophage/monocyte cell lineage. CD169 is preferentially expressed on cells in the late stages of maturation. It is expressed strongly on alveolar and tissue macrophages, but weakly on blood monocytes.
    产品特性
    Synonyms: Sialoadhesin, Siglec-1, Sialic acid-binding Ig-like lectin 1
    纯化方法
    Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
    免疫原
    Porcine alveolar macrophages
    克隆位点
    3B1-11
    亚型
    IgG1
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  • 应用备注
    Flow cytometry: Neat, use 10 μL of the suggested working dilution to label 1x10^6 cells in100 l.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.1 mg/mL
    缓冲液
    PBS, 0.09 % Sodium Azide, 1 % BSA
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2 - 8 °C up to one month or (in aliquots) at -20 °C forlonger. Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.
    Shelf life: one year from despatch.
    有效期
    12 months
  • 抗原
    Sialoadhesin/CD169 (SIGLEC1) (Sialic Acid Binding Ig-Like Lectin 1, Sialoadhesin (SIGLEC1))
    别名
    CD169 / SIGLEC1 (SIGLEC1 产品)
    别名
    Cd169 antibody, Siglec-1 antibody, Sn antibody, CD169 antibody, SIGLEC-1 antibody, SN antibody, dJ1009E24.1 antibody, SA antibody, SIGLEC1 antibody, p210 antibody, pSn antibody, sialic acid binding Ig like lectin 1 antibody, sialic acid binding Ig-like lectin 1, sialoadhesin antibody, SIGLEC1 antibody, Siglec1 antibody
    背景
    Two families of mammalian lectin like adhesion molecules have been shown to bind glycoconjugate ligands in a sialic acid dependent manner: the selectins and the sialoadhesins. The sialoadhesin family has 4 members: CD22, a B cell specific marker, myelin associated glycoprotein (MAG), which is expressed on oligodendrocytes and Schwann cells, CD33, a myeloid differentiation antigen, and sialoadhesin, which is expressed only by a subpopulation of tissue macrophages. Involved in cell-cell interactions, sialoadhesin is structurally related to the 3 other listed members of the sialoadhesin family. CD169 is a sialic acid binding site of sialoadhesin. CD169 is a macrophage receptor expressed on stromal macrophages in many tissues, particularly found in lymph nodes, bone marrow and spleen.Synonyms: Sialic acid-binding Ig-like lectin 1, Sialoadhesin, Siglec-1
    基因ID
    397623
    UniProt
    Q7YRQ7
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