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IL12B 抗体

IL12B 适用: 人, 绵羊, Cow FACS, EIA, Func 宿主: 小鼠 Monoclonal CC326 unconjugated
产品编号 ABIN317391
发货至: 中国
  • 抗原 See all IL12B 抗体
    IL12B (Interleukin 12 beta (IL12B))
    适用
    • 65
    • 37
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    • 1
    • 1
    人, 绵羊, Cow
    宿主
    • 77
    • 20
    • 3
    • 2
    小鼠
    克隆类型
    • 79
    • 23
    单克隆
    标记
    • 61
    • 8
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    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    This IL12B antibody is un-conjugated
    应用范围
    • 78
    • 51
    • 30
    • 13
    • 13
    • 13
    • 13
    • 9
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    • 7
    • 5
    • 3
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    Flow Cytometry (FACS), Enzyme Immunoassay (EIA), Functional Studies (Func)
    特异性
    This antibody recognizes Interleukin-12. It has been shown to block the biological activity of IL-12.
    产品特性
    Synonyms: Interleukin-12B, IL-12B, IL-12 subunit p40, CLMF p40, NKSF2, Cytotoxic lymphocytematuration factor 40 kDa subunit, NK cell stimulatory factor chain 2
    纯化方法
    Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
    免疫原
    Recombinant bovine IL-12
    克隆位点
    CC326
    亚型
    IgG2b
    Top Product
    Discover our top product IL12B Primary Antibody
  • 应用备注
    ELISA: 1/100 - 1/1000. Flow cytometry: 1/1000, use 10 μL to label 10^6 cells of 100 l. Functional assays: 1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS, pH 7.4, None, None
    储存液
    Azide free
    储存条件
    -20 °C
    储存方法
    Store the antibody undiluted at -20 °C. Avoid repeated freezing and thawing.
    Shelf life: One year from despatch.
    有效期
    12 months
  • 抗原
    IL12B (Interleukin 12 beta (IL12B))
    别名
    Interleukin-12 beta / IL12B (IL12B 产品)
    背景
    Interleukin 12 (IL12) can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine activated killer cells, and stimulate the production of IFN gamma by resting PBMC. IL12 induces IFN gamma, TNF alpha production in T and NK cells, costimulation of PBL proliferation, proliferation/differentiation of TH1 T lymphocytes. It is downregulated by IL10, homodimeric p40 antagonistic to functional p70 heterodimer. IL12R beta 1 binds p40 but when dimeric with IL12R beta 2 binds p35.Synonyms: CLMF p40, Cytotoxic lymphocyte maturation factor 40 kDa subunit, IL-12 subunit p40, IL-12B, Interleukin-12B, NK cell stimulatory factor chain 2, NKSF2
    基因ID
    281857
    UniProt
    P46282
    途径
    JAK/STAT Signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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