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IL-4 抗体 (PE)

This anti-IL-4 antibody is a 小鼠 单克隆 antibody detecting IL-4 in FACS. Suitable for 犬, Cow, Pig, 绵羊, 山羊 和 Mustelid.
产品编号 ABIN317378
发货至: 中国

Quick Overview for IL-4 抗体 (PE) (ABIN317378)

抗原

See all IL-4 (IL4) 抗体
IL-4 (IL4) (Interleukin 4 (IL4))

适用

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犬, Cow, Pig, 绵羊, 山羊, Mustelid

宿主

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小鼠

克隆类型

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单克隆

标记

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This IL-4 antibody is conjugated to PE

应用范围

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Flow Cytometry (FACS)

克隆位点

CC303
  • 特异性

    This antibody recognises bovine interleukin 4.

    产品特性

    Synonyms: IL-4, BSF1, Lymphocyte stimulatory factor 1, Binetrakin, Pitrakinra, B-cell stimulatory factor1

    纯化方法

    Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant

    亚型

    IgG2a
  • 应用备注

    Flow Cytometry: 1/5.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 溶解方式

    Reconstitute with 1 mL distilled water

    浓度

    0.1 mg/mL

    缓冲液

    Phosphate buffered saline pH 7.4 containing 0.09 % Sodium Azide, 1 % Bovine Serum Albumin

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
    Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    IL-4 (IL4) (Interleukin 4 (IL4))

    别名

    Interleukin-4 / IL4

    背景

    IL4 is a pleiotropic cytokine produced by activated T cells, mast cells and basophils. It is a ligand for Interleukin 4 receptor. The Interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. IL4 elicits many different biological responses, but has two dominant functions. The first is regulating differentiation of naive CD4+ T cell to the Th2 type. Th2 cells produce IL4, IL5, IL10 and IL13, which tend to favor a humoral immune response while suppressing a cell mediated immune response controlled by Th1 cells. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. The second is regulating IgE and IgG1 production by B cells. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.Synonyms: B-cell stimulatory factor 1, BSF1, Binetrakin, IL-4, Lymphocyte stimulatory factor 1, Pitrakinra

    基因ID

    3565

    UniProt

    P05112

    途径

    JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport, Activated T Cell Proliferation
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