This antibody recognises SIRP gamma, a 55 kDa signal regulatory protein which is a member of the immunoglobulin gene superfamily.
产品特性
Synonyms: SIRP-beta-2, SIRP-b2, SIRPB2, SIRP gamma, Signal-regulatory protein gamma,Signal-regulatory protein beta-2, CD172 antigen-like family member B
纯化方法
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Flow Cytometry: 1/10. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
限制
仅限研究用
浓度
0,1 mg/mL
缓冲液
Phosphate buffered saline pH 7.4 containing 0.09 % Sodium Azide (NaN3) and 1 % Bovine Serum Albumin
储存液
Sodium azide
注意事项
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
4 °C/-20 °C
储存方法
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light. Shelf life: one year from despatch. Caution: (A full Health and Safety assessment is available upon request) This product containsSodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled bytrained staff only.
SIRP gamma, also known as CD172g, is expressed on most T lymphocytes and a subset of B-cells but is absent on myeloid cells. CD172g has a truncated cytoplasmic tail, which is similar to SIRP beta, but unlike SIRP beta CD172g does not require DAP12 for expression at the cell surface. CD172g, like SIRP alpha, binds to CD47 inducing apoptosis. It is also involved in the negative regulation of receptor tyrosine kinase-coupled signalling.Synonyms: CD172 antigen-like family member B, SIRP gamma, SIRP-b2, SIRP-beta-2, SIRPB2, Signal-regulatory protein beta-2, Signal-regulatory protein gamma