PLVAP 抗体 (Biotin)
Quick Overview for PLVAP 抗体 (Biotin) (ABIN316983)
抗原
See all PLVAP 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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产品特性
- Synonyms: Plasmalemma vesicle protein 1, PV1, PV-1, MECA-32 antigen, FELS, Endothelial cell marker,Endothelial cell surface marker, Endothelial Cell Antigen, Plasmalemma vesicle-associatedprotein, Fenestrated endothelial-linked structure protein
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纯化方法
- Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
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亚型
- IgG2a
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应用备注
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Flow Cytometry. Immunohistochemistry on frozen sections: 1/10.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0,1 mg/mL
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缓冲液
- Phosphate buffered saline pH 7.4 containing 0.09 % Sodium Azide (NaN3) and 1 % Bovine Serum Albumin
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
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- PLVAP (Plasmalemma Vesicle Associated Protein (PLVAP))
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别名
- PLVAP
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背景
- PLVAP is a 60kD protein which is otherwise known as MECA-32 and PV-1. PLVAP is a transmembrane homodimer which is associated with endothelial cell caveolae and fenestrae. In adult and embryonic mice, PLVAP is primarily expressed on endothelial tissues but shows restricted distribution in the skeletal, cardiac and brain tissues. In embryonic mice, PLVAP expression, on the vasculature associated with blood brain barrier has been reported to be developmentally regulated. In humans, PLVAP is selectively up-regulated in a variety of high-grade brain tumors, including glioblastoma and metastatic carcinoma, as well as other cerebral disorders associated with blood-brain barrier disruption, such as acute ischemia. PLVAP represents a novel marker of brain tumour angiogenesis and integrity of the blood-brain barrier and is a potential therapeutic target.Synonyms: Endothelial Cell Antigen, Endothelial cell marker, Endothelial cell surface marker, FELS, Fenestrated endothelial-linked structure protein, MECA-32 antigen, PV-1, PV1, Plasmalemma vesicle protein 1, Plasmalemma vesicle-associated protein
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UniProt
- Q9BX97
抗原
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