This antibody is specific for the C-terminal variant of human CDw92 (isoform 3), also known as CTL1. Clone VIM-15b is reported to augment the LPS-induced production of IL-10 by monocyte-derived dendritic cells (Mo-DCs), and the reduced expression of CDw92 by Mo-DCs treated with ionomycin or calcium ionophore, can be reinduced in the presence of IL-10.
产品特性
Synonyms: CDw92, CTL1, Choline transporter-like protein 1, Solute carrier family 44 member 1
纯化方法
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Flow Cytometry: 1/10. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
限制
仅限研究用
溶解方式
Reconstitute with 1.0 mL distilled water
浓度
0,1 mg/mL
缓冲液
Phosphate buffered saline pH 7.4 containing 0.09 % Sodium Azide (NaN3) and 1 % Bovine Serum Albumin
储存液
Sodium azide
注意事项
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
4 °C
储存方法
Prior to and following reconstitution store the antibody at 2-8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light. Shelf life: one year from despatch.
有效期
12 months
抗原
SLC44A1
(Solute Carrier Family 44, Member 1 (SLC44A1))
CDw92 is a 70 kDa multi-pass membrane protein, expressed by monocytes, neutrophils, certain myeloid and T cell lines, and weakly by endothelial cells, fibroblasts and epithelial cells. CDw92 is a member of the choline transporter-like protein family, so called due to their involvement in the efficient supply/transport of the natural amine choline, a vital cell nutrient required for the synthesis of cell membrane phospholipid components and the neurotransmitter acetylcholine.Synonyms: CDw92, CTL1, Choline transporter-like protein 1, Solute carrier family 44 member 1