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PD-1 抗体

This anti-PD-1 antibody is a 大鼠 单克隆 antibody detecting PD-1 in FACS. Suitable for 小鼠.
产品编号 ABIN316895
发货至: 中国

Quick Overview for PD-1 抗体 (ABIN316895)

抗原

See all PD-1 (PDCD1) 抗体
PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

适用

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小鼠

宿主

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大鼠

克隆类型

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单克隆

标记

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This PD-1 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS)

克隆位点

RMP1-30
  • 特异性

    This antibody recognises CD279, a 55 kDa cell surface protein which is a member of the CD28/CTLA-4 family, otherwise known as Programmed Death-1 (PD-1). Antibodies produced by clone RMP1-30 do not block the binding of both B7-H1-Ig and B7-DC-Ig fusion proteins to PD-1 transfected BHK cells.

    产品特性

    Synonyms: Protein PD-1, hPD-1, PDCD1, Programmed cell death protein 1

    纯化方法

    Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant

    免疫原

    PD-1 transferred BHK cells

    亚型

    IgG2b
  • 应用备注

    Flow Cytometry: 1/100 - 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS, pH 7.4, 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch. Caution: (A full Health and Safety assessment is available upon request) This product containsSodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled bytrained staff only.

    有效期

    12 months
  • 抗原

    PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

    别名

    CD279 / PD1

    背景

    CD279 is expressed predominantly on activated T- and B- lymphocytes and on a subset of thymocytes. Studies suggest that CD279, an immunoinhibitory receptor, plays a critical role in peripheral tolerance induction and prevention of autoimmune disease. Two members of the B7 family, B7-H1 (PD-L1) and B7-DC (PD-L2), have been identified as the ligands for CD279.Synonyms: PDCD1, Programmed cell death protein 1, Protein PD-1, hPD-1

    基因ID

    18566

    UniProt

    Q02242

    途径

    Cancer Immune Checkpoints
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